Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

1295

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P03385 (Created: 1986-07-21 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_MLVMO

Protein Name

Envelope glycoprotein

Gene

env

Organism Scientific

Moloney murine leukemia virus

Organism Common

MoMLV

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Gammaretrovirus
          Murine leukemia virus

Protein Length [aa]

665

Protein Mass [Da]

73302

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   33
chain   Envelope glycoprotein      34   665
chain   Surface protein   by similarity   34   469
chain   Transmembrane protein      470   649
disulfide bond      by similarity   79   129
disulfide bond      by similarity   105   118
disulfide bond      by similarity   106   114
disulfide bond      by similarity   152   172
disulfide bond      by similarity   164   177
disulfide bond      by similarity   209   215
disulfide bond   Interchain (between SU and TM chains, or C-339 with C-563); alternate      336   563
disulfide bond   Alternate      336   339
disulfide bond      by similarity   366   420
disulfide bond      by similarity   385   397
disulfide bond      by similarity   427   440
disulfide bond      by similarity   555   562
transmembrane region      potential   611   631
topological domain   Extracellular   potential   1   610
topological domain   Cytoplasmic   potential   632   665
region of interest   Fusion peptide   by similarity   472   492
region of interest   Immunosuppression   by similarity   538   554
glycosylation site   N-linked (GlcNAc...)   by similarity   45   45
glycosylation site   N-linked (GlcNAc...)   by similarity   199   199
glycosylation site   N-linked (GlcNAc...)   by similarity   326   326
glycosylation site   N-linked (GlcNAc...)   potential   358   358
glycosylation site   N-linked (GlcNAc...)   potential   365   365
glycosylation site   N-linked (GlcNAc...)   potential   398   398
glycosylation site   N-linked (GlcNAc...)   potential   434   434
helix         516   547
helix         549   551
helix         554   558
site   Cleavage; by host      469   470
site   Cleavage; by viral protease   by similarity   649   650
metal ion-binding site   Zinc   by similarity   117   117
short sequence motif   CXXC      336   339
short sequence motif   CX6CC      555   563
short sequence motif   YXXL motif; contains endocytosis signal   by similarity   655   658
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   630   630
peptide   R-peptide. /FTId=PRO_0000040767      650   665
coiled-coil region      potential   500   549
coiled-coil region      potential   559   595

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MARSTLSKPLKNKVNPRGPLIPLILLMLRGVST

Sequence

MARSTLSKPLKNKVNPRGPLIPLILLMLRGVSTASPGSSPHQVYNITWEV
TNGDRETVWATSGNHPLWTWWPDLTPDLCMLAHHGPSYWGLEYQSPFSSP
PGPPCCSGGSSPGCSRDCEEPLTSLTPRCNTAWNRLKLDQTTHKSNEGFY
VCPGPHRPRESKSCGGPDSFYCAYWGCETTGRAYWKPSSSWDFITVNNNL
TSDQAVQVCKDNKWCNPLVIRFTDAGRRVTSWTTGHYWGLRLYVSGQDPG
LTFGIRLRYQNLGPRVPIGPNPVLADQQPLSKPKPVKSPSVTKPPSGTPL
SPTQLPPAGTENRLLNLVDGAYQALNLTSPDKTQECWLCLVAGPPYYEGV
AVLGTYSNHTSAPANCSVASQHKLTLSEVTGQGLCIGAVPKTHQALCNTT
QTSSRGSYYLVAPTGTMWACSTGLTPCISTTILNLTTDYCVLVELWPRVT
YHSPSYVYGLFERSNRHKREPVSLTLALLLGGLTMGGIAAGIGTGTTALM
ATQQFQQLQAAVQDDLREVEKSISNLEKSLTSLSEVVLQNRRGLDLLFLK
EGGLCAALKEECCFYADHTGLVRDSMAKLRERLNQRQKLFESTQGWFEGL
FNRSPWFTTLISTIMGPLIVLLMILLFGPCILNRLVQFVKDRISVVQALV
LTQQYHQLKPIEYEP

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website