Signal Peptide Database - Viruses

 Entry Details
ID   1296
Source Database   UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number   P05886    (Created: 1988-11-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name   ENV_SIVVT
Protein Name   Envelope glycoprotein gp160
Gene   env
Organism Scientific   Simian immunodeficiency virus agm.vervet (isolate AGM TYO-1)
Organism Common   SIV-agm.ver
Lineage   Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Primate lentivirus group
Protein Length [aa]   865
Protein Mass [Da]   99026
Features  
TypeDescriptionStatusStartEnd
signal peptide      potential   1   20
chain   Envelope glycoprotein gp160      21   865
chain   Surface protein   by similarity   21   536
chain   Transmembrane protein   by similarity   537   865
disulfide bond      by similarity   42   55
disulfide bond      by similarity   101   218
disulfide bond      by similarity   108   209
disulfide bond      by similarity   113   166
disulfide bond      by similarity   231   261
disulfide bond      by similarity   241   253
disulfide bond      by similarity   311   344
disulfide bond      by similarity   396   471
transmembrane region      potential   706   726
topological domain   Extracellular   potential   21   705
topological domain   Cytoplasmic   potential   727   865
region of interest   V1      113   165
region of interest   V2      166   209
region of interest   V3      311   343
region of interest   V4      403   444
region of interest   V5      487   494
region of interest   Fusion peptide   potential   537   557
region of interest   Immunosuppression   by similarity   600   616
glycosylation site   N-linked (GlcNAc...)   potential   35   35
glycosylation site   N-linked (GlcNAc...)   potential   68   68
glycosylation site   N-linked (GlcNAc...)   potential   117   117
glycosylation site   N-linked (GlcNAc...)   potential   150   150
glycosylation site   N-linked (GlcNAc...)   potential   165   165
glycosylation site   N-linked (GlcNAc...)   potential   195   195
glycosylation site   N-linked (GlcNAc...)   potential   198   198
glycosylation site   N-linked (GlcNAc...)   potential   210   210
glycosylation site   N-linked (GlcNAc...)   potential   252   252
glycosylation site   N-linked (GlcNAc...)   potential   255   255
glycosylation site   N-linked (GlcNAc...)   potential   266   266
glycosylation site   N-linked (GlcNAc...)   potential   276   276
glycosylation site   N-linked (GlcNAc...)   potential   282   282
glycosylation site   N-linked (GlcNAc...)   potential   294   294
glycosylation site   N-linked (GlcNAc...)   potential   306   306
glycosylation site   N-linked (GlcNAc...)   potential   316   316
glycosylation site   N-linked (GlcNAc...)   potential   373   373
glycosylation site   N-linked (GlcNAc...)   potential   414   414
glycosylation site   N-linked (GlcNAc...)   potential   451   451
glycosylation site   N-linked (GlcNAc...)   potential   488   488
glycosylation site   N-linked (GlcNAc...)   potential   491   491
glycosylation site   N-linked (GlcNAc...)   potential   645   645
glycosylation site   N-linked (GlcNAc...)   potential   661   661
site   Cleavage; by host furin   potential   536   537
site   In-frame UAG termination codon      770   770
short sequence motif   YXXL motif; contains endocytosis signal   by similarity   732   735
coiled-coil region      potential   566   616
coiled-coil region      potential   653   687
SP Length   20
 ----+----1----+----2----+----3----+----4----+----5
Signal Peptide MRYTIITLGIIVIGIGIVLS
Sequence MRYTIITLGIIVIGIGIVLSKQWITVFYGIPVWKNSSVQAFCMTPTTSLW
ATTNCIPDDHDYTEVPL
NITEPFEAWGDRNPLIAQAASNIHLLFEQTMKP
CVKLSPLCIKMN
CVELNSTRERATTPTTTPKSTGLPCVGPTSGENLQSCN
ASIIEREMEDEPASNCTFAMAGYVRDQKKNYYSVVWNDAEIYCKNKTNST
SKECYMIHC
NDSVIKEACDKTYWDQLRLRYCAPAGYALLKCNDEDYNGYK
Q
NCSNVSVVHCTGLMNTTVTTGLLLNGSYHENRTQIWQKHRVNNNTVLIL
FNKHY
NLSVTCRRPGNKTVLPVTIMAGLVFHSQKYNMKLRQAWCHFEGNW
RGAWREVKQKIVELPKDRYKGT
NNTEHIYLQRQWGDPEASNLWFNCQGEF
FY
CKMDWFLNYLNNKTWDAYHNFCSSKKKGHAPGPCVQRTYVAYHIRSVI
NDSYTLSKKTYAPPREGHLQCRSTVTGMTVELNYNSKNRTNVTLSPQIES
IWAAELGRYKLVEITPIGFAPTEVRRYTGGHERQK
RVPFVLGFLGFLGAA
GTAMGAA
ASSLTVQSRHLLAGILQQQKNLLAAVEAQQQMLKLTIWGVKNL
NARVTALEKYLEDQAR
LNSWGCAWKQVCHTTVEWPWTNRTPDWQNMTWLE
WE
RQIADLESNITGQLVKAREQEEKNLDAYQKLTSWSDFWSWFDFSKWLN
ILKMG
FLVIVGIIGLRLLYTVYGCIVRVRQGYVPLSPQIHIHQVGKGRPD
NADEPGEGGDNSRIKLESW
XKDSKSRCMQLTAWLTRLNTWLYNSCLTLLI
QLRKAFQYLQYGLAELKTGAQEILQTLAGVAQNACHQIWLACRSAYRNIV
NSPRRVRQGLEEILN
Original MRYTIITLGIIVIGIGIVLSKQWITVFYGIPVWKNSSVQAFCMTPTTSLW
ATTNCIPDDHDYTEVPLNITEPFEAWGDRNPLIAQAASNIHLLFEQTMKP
CVKLSPLCIKMNCVELNSTRERATTPTTTPKSTGLPCVGPTSGENLQSCN
ASIIEREMEDEPASNCTFAMAGYVRDQKKNYYSVVWNDAEIYCKNKTNST
SKECYMIHCNDSVIKEACDKTYWDQLRLRYCAPAGYALLKCNDEDYNGYK
QNCSNVSVVHCTGLMNTTVTTGLLLNGSYHENRTQIWQKHRVNNNTVLIL
FNKHYNLSVTCRRPGNKTVLPVTIMAGLVFHSQKYNMKLRQAWCHFEGNW
RGAWREVKQKIVELPKDRYKGTNNTEHIYLQRQWGDPEASNLWFNCQGEF
FYCKMDWFLNYLNNKTWDAYHNFCSSKKKGHAPGPCVQRTYVAYHIRSVI
NDSYTLSKKTYAPPREGHLQCRSTVTGMTVELNYNSKNRTNVTLSPQIES
IWAAELGRYKLVEITPIGFAPTEVRRYTGGHERQKRVPFVLGFLGFLGAA
GTAMGAAASSLTVQSRHLLAGILQQQKNLLAAVEAQQQMLKLTIWGVKNL
NARVTALEKYLEDQARLNSWGCAWKQVCHTTVEWPWTNRTPDWQNMTWLE
WERQIADLESNITGQLVKAREQEEKNLDAYQKLTSWSDFWSWFDFSKWLN
ILKMGFLVIVGIIGLRLLYTVYGCIVRVRQGYVPLSPQIHIHQVGKGRPD
NADEPGEGGDNSRIKLESWXKDSKSRCMQLTAWLTRLNTWLYNSCLTLLI
QLRKAFQYLQYGLAELKTGAQEILQTLAGVAQNACHQIWLACRSAYRNIV
NSPRRVRQGLEEILN
 ----+----1----+----2----+----3----+----4----+----5
Hydropathies  
 

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