Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

1415

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P31615 (Created: 1993-07-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_CVMA5

Protein Name

Hemagglutinin-esterase

Gene

Organism Scientific

Murine coronavirus (strain A59)

Organism Common

MHV-A59

Lineage

Viruses
  ssRNA positive-strand viruses, no DNA stage
    Nidovirales
      Coronaviridae
        Coronavirus
          Coronavirus group 2
            Coronavirus group 2a

Protein Length [aa]

428

Protein Mass [Da]

47808

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   20
chain   Hemagglutinin-esterase      21   428
transmembrane region      potential   405   425
topological domain   Extracellular   potential   21   404
topological domain   Cytoplasmic   potential   426   428
region of interest   Esterase domain first part   by similarity   9   129
region of interest   Receptor binding   by similarity   130   278
region of interest   Esterase domain second part   by similarity   279   392
glycosylation site   N-linked (GlcNAc...)   potential   91   91
glycosylation site   N-linked (GlcNAc...)   potential   149   149
glycosylation site   N-linked (GlcNAc...)   potential   193   193
glycosylation site   N-linked (GlcNAc...)   potential   243   243
glycosylation site   N-linked (GlcNAc...)   potential   313   313
glycosylation site   N-linked (GlcNAc...)   potential   328   328
glycosylation site   N-linked (GlcNAc...)   potential   332   332
glycosylation site   N-linked (GlcNAc...)   potential   357   357
glycosylation site   N-linked (GlcNAc...)   potential   371   371
active site   Nucleophile   by similarity   42   42
active site   Charge relay system   by similarity   235   235
active site   Charge relay system   by similarity   342   342

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MCIAMAPRTLLLLIXCQLVF

Sequence

MCIAMAPRTLLLLIXCQLVFGFNEPLNIVSHLNDDWFLFGDSRSDCTYVE
NNGHPKLDWLDLDPKLCNSGKISAKSGNSLFRSFHFTDFYNYTGEGDQIV
FYEGVNFSPSHGFKCLAHGDNKRWMGNKARFYARVYEKMAQYRSLSFVNV
SYAYGGNAKPASICKDNTLTLNNPTFISKESNYVDYYYESEANFTLEGCD
EFIVPLCGFNGHSKGSSSDAANKYYTDSQSYYNMDIGVLYGFNSTLDVGN
TAKDPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLHKTKRFMPVQV
VDSRWSSIRQSDNMTAAACQLPYCFFRNTSANYSGGTHDAHHGDFHFRQL
LSGLLYNVSCIAQQGAFLYNNVSSSWPAYGYGHCPTAANIGYMAPVCIYD
PLPVILLGVLLGIAVLIIVFLNVLFYDG

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website