Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

1416

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P03459 (Created: 1986-07-21 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I34A0

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Fowl plague virus/Rostock/8/1934 H7N1)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

563

Protein Mass [Da]

62703

Features

TypeDescriptionStatusStartEnd
signal peptide         1   18
chain   Hemagglutinin HA1 chain      19   336
chain   Hemagglutinin HA2 chain      343   563
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   22   479
disulfide bond      by similarity   60   286
disulfide bond      by similarity   72   84
disulfide bond      by similarity   105   147
disulfide bond      by similarity   290   314
disulfide bond      by similarity   486   490
transmembrane region      potential   530   550
topological domain   Extracellular   potential   19   529
topological domain   Cytoplasmic   potential   551   563
glycosylation site   N-linked (GlcNAc...)      30   30
glycosylation site   N-linked (GlcNAc...)      46   46
glycosylation site   N-linked (GlcNAc...)      141   141
glycosylation site   N-linked (GlcNAc...)      167   167
glycosylation site   N-linked (GlcNAc...)      249   249
glycosylation site   N-linked (GlcNAc...) (high mannose)      424   424
glycosylation site   N-linked (GlcNAc...); in mutant ts227      475   475
glycosylation site   N-linked (GlcNAc...) (high mannose)      496   496
sequence variant   (in strain: mutant ts1)      0   0
sequence variant   (in strain: mutant ts1)      0   0
sequence variant   (in strain: mutant ts227)      0   0
sequence variant   (in strain: mutant ts227)      0   0
site   Cleavage; by host   by similarity   342   343
propeptide   Connecting peptide      337   342
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   551   551
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   559   559
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   562   562

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MNTQILVFALVAVIPTNA

Sequence

MNTQILVFALVAVIPTNADKICLGHHAVSNGTKVNTLTERGVEVVNATET
VERTNIPKICSKGKRTTDLGQCGLLGTITGPPQCDQFLEFSADLIIERRE
GNDVCYPGKFVNEEALRQILRGSGGIDKETMGFTYSGIRTNGTTSACRRS
GSSFYAEMEWLLSNTDNASFPQMTKSYKNTRRESALIVWGIHHSGSTTEQ
TKLYGSGNKLITVGSSKYHQSFVPSPGTRPQINGQSGRIDFHWLILDPND
TVTFSFNGAFIAPNRASFLRGKSMGIQSDVQVDANCEGECYHSGGTITSR
LPFQNINSRAVGKCPRYVKQESLLLATGMKNVPEPSKKREKRGLFGAIAG
FIENGWEGLVDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEK
TNQQFELIDNEFTEVEKQIGNLINWTKDFITEVWSYNAELLVAMENQHTI
DLADSEMNKLYERVRKQLRENAEEDGTGCFEIFHKCDDDCMASIRNNTYD
HSKYREEAMQNRIQIDPVKLSSGYKDVILWFSFGASCFLLLAIAVGLVFI
CVKNGNMRCTICI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website