Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

2418

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q80A30 (Created: 2007-11-13 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I01A1

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Chicken/Hong Kong/YU562/2001 H5N1 genotype B)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

552

Protein Mass [Da]

62439

Features

TypeDescriptionStatusStartEnd
signal peptide         1   5
chain   Hemagglutinin HA1 chain      6   327
chain   Hemagglutinin HA2 chain      336   552
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   9   472
disulfide bond      by similarity   47   279
disulfide bond      by similarity   60   72
disulfide bond      by similarity   95   140
disulfide bond      by similarity   283   307
disulfide bond      by similarity   479   483
transmembrane region      potential   521   541
topological domain   Extracellular   potential   6   520
topological domain   Cytoplasmic   potential   542   552
glycosylation site   N-linked (GlcNAc...)   potential   15   15
glycosylation site   N-linked (GlcNAc...)   potential   16   16
glycosylation site   N-linked (GlcNAc...)   potential   28   28
glycosylation site   N-linked (GlcNAc...)   potential   170   170
glycosylation site   N-linked (GlcNAc...)   potential   291   291
glycosylation site   N-linked (GlcNAc...)   potential   489   489
site   Cleavage; by host   by similarity   335   336
propeptide   Connecting peptide      328   335
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   546   546
non-terminal residue         1   1
non-terminal residue         552   552

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

SLVKS

Sequence

SLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLD
GVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKASPANDLCYPGDF
NDYEELKHLLSRINHFEKIQIIPKSSWSNHEASSGVSSACPYLGKSSFFR
NVVWLIKKNSAYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPT
TYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDAINFESNG
NFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSSMPFHNIH
PLTIGECPKYVKSNRLVLATGLRNTPQRERRRKKRGLFGAIAGFIEGGWQ
GMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEA
VGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNV
KNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVKNGTYDYPQYSEE
ARLNREEISGVKLESMGTYQILSIYSTVASSLTLAIMVAGLSLWMCSNGS
LQ

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website