Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

2421

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P26138 (Created: 1992-05-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I78A4

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Mallard/New York/6874/1978 H3N2)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

566

Protein Mass [Da]

63574

Features

TypeDescriptionStatusStartEnd
signal peptide         1   16
chain   Hemagglutinin HA1 chain      17   344
chain   Hemagglutinin HA2 chain      346   566
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   30   482
disulfide bond      by similarity   68   293
disulfide bond      by similarity   80   92
disulfide bond      by similarity   113   155
disulfide bond      by similarity   297   321
disulfide bond      by similarity   489   493
transmembrane region      potential   531   551
topological domain   Extracellular   potential   17   530
topological domain   Cytoplasmic   potential   552   566
glycosylation site   N-linked (GlcNAc...)   potential   24   24
glycosylation site   N-linked (GlcNAc...)   potential   38   38
glycosylation site   N-linked (GlcNAc...)   potential   54   54
glycosylation site   N-linked (GlcNAc...)   potential   181   181
glycosylation site   N-linked (GlcNAc...)   potential   301   301
glycosylation site   N-linked (GlcNAc...)   potential   499   499
site   Cleavage; by host   by similarity   345   346
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   555   555
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   562   562
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   565   565

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKTIIVLSCFFCLAFS

Sequence

MKTIIVLSCFFCLAFSQDLSENNNNTATLCLGHHAVPNGTIVKTITDDQI
EVTNATELVQSSSTGKICNNPHRILDGRDCTLIDALLGDPHCDVFQDETW
DLYVERSKSFSNCYPYDVPDYASLRSLVASSGTLEFITEAFTWTGVTQNG
GSGACKRGPGNGFFSRLNWLTKSGSAYPVLNVTMPNNDNFDKLYVWGVHH
PSTNQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSRRISIYW
TIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITP
NGSIPNDKPFQNVNKITYGACPKYIKQSTLKLATGMRNVPEKQTRGLFGA
IAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRV
IEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQ
HTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNG
TYDHDIYRDEALNNRFQIKGCGVKSGYKDWILWISFAISCFLLCVVLLGF
IMWACQRGNIRCNICI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website