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Signal Peptide Database - Mammalia
Entry Details
ID
11
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P23795 (Created: 1991-11-01 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
ACES_BOVIN
Protein Name
Acetylcholinesterase
Gene
ACHE
Organism Scientific
Bos taurus
Organism Common
Bovine
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Laurasiatheria
Cetartiodactyla
Ruminantia
Pecora
Bovidae
Bovinae
Bos
Protein Length [aa]
613
Protein Mass [Da]
67664
Features
Type
Description
Status
Start
End
signal peptide
1
30
chain
Acetylcholinesterase
31
613
disulfide bond
by similarity
99
126
disulfide bond
by similarity
287
302
disulfide bond
by similarity
439
559
disulfide bond
Interchain
by similarity
610
610
glycosylation site
N-linked (GlcNAc...)
probable
91
91
glycosylation site
N-linked (GlcNAc...)
probable
295
295
glycosylation site
N-linked (GlcNAc...)
probable
380
380
glycosylation site
N-linked (GlcNAc...)
probable
494
494
active site
Acyl-ester intermediate
by similarity
233
233
active site
Charge relay system
by similarity
364
364
active site
Charge relay system
by similarity
477
477
splice variant
(in isoform H)
0
0
SP Length
30
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEA
Sequence
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEA
EGPEDPELLVMVRGGRLRGL
RLMAPRGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWPGVL
N
ATAFQSV
CY
QYVDTLYPGFEGTEMWNPNRELSEDC
LYLNVWTPYPRPSSPTPVLVWIYG
GGFYSGASSLDVYDGRFLTQAEGTVLVSMNYRVGAFGFLALPGSREAPGN
VGLLDQRLALQWVQENVAAFGGDPTSVTLFGE
S
AGAASVGMHLLSPPSRG
LFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVG
CPPGGAGG
N
DTELV
AC
LRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGD
FHGLQVLVGVVKD
E
GSYFLVYGAPGFSKD
N
ESLISRAQFLAGVRVGVPQA
SDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVV
CPVAQLAGRLAA
QGARVYAYIFEHRASTLSWPLWMGVP
H
GYEIEFIFGLPLEPSL
N
YTIEER
TFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQYVSLNLRPLEV
RRGLRAQAC
AFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDR
C
SDL
Original
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGL
RLMAPRGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCY
QYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPSSPTPVLVWIYG
GGFYSGASSLDVYDGRFLTQAEGTVLVSMNYRVGAFGFLALPGSREAPGN
VGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRG
LFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGD
FHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQA
SDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA
QGARVYAYIFEHRASTLSWPLWMGVPHGYEIEFIFGLPLEPSLNYTIEER
TFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQYVSLNLRPLEV
RRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11