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Signal Peptide Database - Mammalia
Entry Details
ID
110
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P61276 (Created: 2004-05-10 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
CATK_MACFA
Protein Name
Cathepsin K
Gene
CTSK
Organism Scientific
Macaca fascicularis
Organism Common
Crab eating macaque
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Euarchontoglires
Primates
Haplorrhini
Catarrhini
Cercopithecidae
Cercopithecinae
Macaca
Protein Length [aa]
329
Protein Mass [Da]
36942
Features
Type
Description
Status
Start
End
signal peptide
potential
1
15
chain
Cathepsin K
115
329
disulfide bond
by similarity
136
177
disulfide bond
by similarity
170
210
disulfide bond
by similarity
269
318
glycosylation site
N-linked (GlcNAc...)
potential
103
103
active site
by similarity
139
139
active site
by similarity
276
276
active site
by similarity
296
296
propeptide
Activation peptide
16
114
SP Length
15
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MWGLKVLLLPVMSFA
Sequence
MWGLKVLLLPVMSFA
LYPEEILDTHWELWKKTHRKQYNSKVDEISRRLIW
EKNLKYISIHNLEASLGVHTYELAMNHLGDMTNEEVVQKMTGLKVPASHS
RSNDTLYIPDWEGR
APDSVDYRKKGYVTPVKNQGQ
CGS
C
WAFSSVGALEG
QLKKKTGKLLNLSPQNLVD
CVSENDGCGGGYMTNAFQYVQKNRGIDSEDA
YPYVGQEESC
MYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAID
ASLTSFQFYSKGVYYDES
CNSDNLN
H
AVLAVGYGIQKGNKHWIIK
N
SWGE
NWGNKGYILMARNKNNAC
GIANLASFPKM
Original
MWGLKVLLLPVMSFALYPEEILDTHWELWKKTHRKQYNSKVDEISRRLIW
EKNLKYISIHNLEASLGVHTYELAMNHLGDMTNEEVVQKMTGLKVPASHS
RSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEG
QLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDA
YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAID
ASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11