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Signal Peptide Database - Viruses
Entry Details
ID
1291
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P31626 (Created: 1993-07-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
ENV_CAEVC
Protein Name
Envelope glycoprotein
Gene
env
Organism Scientific
Caprine arthritis encephalitis virus (strain Cork)
Organism Common
CAEV-Co
Lineage
Viruses
Retro-transcribing viruses
Retroviridae
Orthoretrovirinae
Lentivirus
Ovine/caprine lentivirus group
Protein Length [aa]
966
Protein Mass [Da]
110291
Features
Type
Description
Status
Start
End
signal peptide
by similarity
1
83
chain
Envelope glycoprotein
84
966
chain
Surface protein
by similarity
84
632
chain
Transmembrane protein
by similarity
633
966
transmembrane region
potential
802
822
topological domain
Extracellular
potential
84
801
topological domain
Cytoplasmic
potential
823
966
region of interest
Fusion peptide
potential
633
653
region of interest
Immunosuppression
by similarity
699
715
glycosylation site
N-linked (GlcNAc...)
potential
101
101
glycosylation site
N-linked (GlcNAc...)
potential
134
134
glycosylation site
N-linked (GlcNAc...)
potential
179
179
glycosylation site
N-linked (GlcNAc...)
potential
220
220
glycosylation site
N-linked (GlcNAc...)
potential
231
231
glycosylation site
N-linked (GlcNAc...)
potential
334
334
glycosylation site
N-linked (GlcNAc...)
potential
351
351
glycosylation site
N-linked (GlcNAc...)
potential
357
357
glycosylation site
N-linked (GlcNAc...)
potential
382
382
glycosylation site
N-linked (GlcNAc...)
potential
403
403
glycosylation site
N-linked (GlcNAc...)
potential
407
407
glycosylation site
N-linked (GlcNAc...)
potential
438
438
glycosylation site
N-linked (GlcNAc...)
potential
443
443
glycosylation site
N-linked (GlcNAc...)
potential
449
449
glycosylation site
N-linked (GlcNAc...)
potential
459
459
glycosylation site
N-linked (GlcNAc...)
potential
469
469
glycosylation site
N-linked (GlcNAc...)
potential
483
483
glycosylation site
N-linked (GlcNAc...)
potential
495
495
glycosylation site
N-linked (GlcNAc...)
potential
505
505
glycosylation site
N-linked (GlcNAc...)
potential
511
511
glycosylation site
N-linked (GlcNAc...)
potential
529
529
glycosylation site
N-linked (GlcNAc...)
potential
536
536
site
Cleavage; by host
by similarity
632
633
coiled-coil region
potential
665
715
coiled-coil region
potential
756
791
SP Length
83
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MDAGARYMRLTGKENWVEVTMDGEKERKREGFTAGQQGKYNPQVSKNIGN
RNTNDCFAYKGIFLWRISLTMWILLGINMCVSA
Sequence
MDAGARYMRLTGKENWVEVTMDGEKERKREGFTAGQQGKYNPQVSKNIGN
RNTNDCFAYKGIFLWRISLTMWILLGINMCVSA
EDYITLISDPYGFSPIK
N
VSGVPVTCVTKEFAKWGCQPLGAYPDPEIEYR
N
VSQEVVKEVYQENWPW
NTYHWPLWQMENVRYWLKENMQENQQRK
N
NTKEGIEELLAGTIRGRFCVP
YPFALLKCTKWCWYTAAIN
N
ESGKAGKIKI
N
CTEARAVSCTEDMPLASIQ
RAYWDEKDRESMAFMNIKACDSNLRCQKRPGGCMEGYPIPVGAEIIPESM
KYLRGAKSQYGGIKDKNGELKLPLTLRVWVKLA
N
VSEWVNGTPPDWQDRI
N
GSKGI
N
GTLWGELNSMHHLGFALSQNGKWC
N
YTGEIKLGQETFQYHYKP
NW
N
CTG
N
WTQYPVWQVIRNLDMVEHMTGECVQRPQRH
N
ITVG
N
GTITG
N
C
STTNWDGC
N
CSRSGNYLY
N
SSEGGLLLILCRQ
N
STLTRILGTNT
N
WTTMW
GIYK
N
CSGCE
N
ATLDNTGEGTLGGVANK
N
CSLPHK
N
ESNKWTCAPRQRDG
KTDSLYIAGGKKFWTRIKAQFSCESNIGQLDGMLHQQILLQKYQVIKVRA
YTYGVIEMPENYAKTRIINRKKRELSHKRKK
RG
VGLVIMLVIMAIVAAAG
ASL
GVANAIQQSYT
KAAVQTLANATAAQQDVLEATYAMVQHVAKGVRILE
ARVARVEAITDRIML
YQELDCWHYHQYCITSTKTEVAKYINWTRFKDNCT
WQQWE
RGLQGYDTNLTILLKESAAMTQLAEEQARRIPEVWE
SLKDVFDWS
G
WFSWLKYIPIIVVGLLGCILI
RAVICVCQPLVEIYRTLSTPTYQRVTVI
METRADVAGENQDFGDGLEESDNSETSERVTVQKAWSRAWELWQNSPWKE
PWKRGLLRLLVLPLTMGIWINGWLGEHHKNKKRKGGLETWHKKGTDIGLG
QIPVDHLWCYKKSKSL
Original
MDAGARYMRLTGKENWVEVTMDGEKERKREGFTAGQQGKYNPQVSKNIGN
RNTNDCFAYKGIFLWRISLTMWILLGINMCVSAEDYITLISDPYGFSPIK
NVSGVPVTCVTKEFAKWGCQPLGAYPDPEIEYRNVSQEVVKEVYQENWPW
NTYHWPLWQMENVRYWLKENMQENQQRKNNTKEGIEELLAGTIRGRFCVP
YPFALLKCTKWCWYTAAINNESGKAGKIKINCTEARAVSCTEDMPLASIQ
RAYWDEKDRESMAFMNIKACDSNLRCQKRPGGCMEGYPIPVGAEIIPESM
KYLRGAKSQYGGIKDKNGELKLPLTLRVWVKLANVSEWVNGTPPDWQDRI
NGSKGINGTLWGELNSMHHLGFALSQNGKWCNYTGEIKLGQETFQYHYKP
NWNCTGNWTQYPVWQVIRNLDMVEHMTGECVQRPQRHNITVGNGTITGNC
STTNWDGCNCSRSGNYLYNSSEGGLLLILCRQNSTLTRILGTNTNWTTMW
GIYKNCSGCENATLDNTGEGTLGGVANKNCSLPHKNESNKWTCAPRQRDG
KTDSLYIAGGKKFWTRIKAQFSCESNIGQLDGMLHQQILLQKYQVIKVRA
YTYGVIEMPENYAKTRIINRKKRELSHKRKKRGVGLVIMLVIMAIVAAAG
ASLGVANAIQQSYTKAAVQTLANATAAQQDVLEATYAMVQHVAKGVRILE
ARVARVEAITDRIMLYQELDCWHYHQYCITSTKTEVAKYINWTRFKDNCT
WQQWERGLQGYDTNLTILLKESAAMTQLAEEQARRIPEVWESLKDVFDWS
GWFSWLKYIPIIVVGLLGCILIRAVICVCQPLVEIYRTLSTPTYQRVTVI
METRADVAGENQDFGDGLEESDNSETSERVTVQKAWSRAWELWQNSPWKE
PWKRGLLRLLVLPLTMGIWINGWLGEHHKNKKRKGGLETWHKKGTDIGLG
QIPVDHLWCYKKSKSL
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
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, Dresden, Germany, last update 2010-06-11