Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

1719

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9V4A7 (Created: 2006-09-05 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

PLXB_DROME

Protein Name

Plexin-B

Gene

plexB

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

2051

Protein Mass [Da]

231680

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   33
chain   Plexin-B      34   2051
transmembrane region      potential   1381   1401
topological domain   Extracellular   potential   34   1380
topological domain   Cytoplasmic   potential   1402   2051
domain   Sema      61   533
domain   PSI 1      535   587
domain   PSI 2      683   730
domain   PSI 3      834   880
domain   IPT/TIG 1      888   975
domain   IPT/TIG 2      977   1064
domain   IPT/TIG 3      1097   1193
region of interest   Interaction with PlexA      1402   1784
region of interest   Interaction with activated Rac1 and Rac2      1722   1728
region of interest   Interaction with Rho1      1788   1827
glycosylation site   N-linked (GlcNAc...)   potential   68   68
glycosylation site   N-linked (GlcNAc...)   potential   198   198
glycosylation site   N-linked (GlcNAc...)   potential   276   276
glycosylation site   N-linked (GlcNAc...)   potential   400   400
glycosylation site   N-linked (GlcNAc...)   potential   455   455
glycosylation site   N-linked (GlcNAc...)   potential   541   541
glycosylation site   N-linked (GlcNAc...)   potential   863   863
glycosylation site   N-linked (GlcNAc...)   potential   1053   1053
glycosylation site   N-linked (GlcNAc...)   potential   1092   1092
glycosylation site   N-linked (GlcNAc...)   potential   1140   1140
glycosylation site   N-linked (GlcNAc...)   potential   1181   1181
glycosylation site   N-linked (GlcNAc...)   potential   1307   1307
glycosylation site   N-linked (GlcNAc...)   potential   1316   1316
coiled-coil region      potential   1402   1451

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MLRKELYCANIIHVLHVLCIIIILGSQHYCVNC

Sequence

MLRKELYCANIIHVLHVLCIIIILGSQHYCVNCIEELPAQALSPLNDIVA
QFNLPSIPVQSTASSYGNRSIGNNIESVRDSQSKNYFTHMSFDFMHNVLF
AGATNKILKLNENLRVLAEAVTGPLHDSPQCHAGGCPEDIETSLVNNFNK
ILVVSYAHDGILIACGSIRQGACEIYSLPRFPATPQFFAVPLAANDENAS
TYAFVGPARYAWKEEDILYVGTTFTNVGDYRHDVPAISSRRLDDLNYAEF
SIQQSIINIDVKYRDHFLVDYIYGFNSSEYAYFIIVQKKSHLADEAGYVT
RLARICITDPNYDSYTEITVQCTATENNVDYNIVRDAKVTPASHKLAQKM
GIKKDDHVLVTVFSPSREISNQPESKSAMCIYSIKDIEDMFIENIHLCFN
GTTKDRNLGYISGTINDGRCPIVGSLGNIYNFCSVGLKISGVSPITAHAL
FHFDNVSVTSVTATSTTDQQHSLAFLGTNMGVIKKVLLSGQSPGEYEEIV
VDAGNRILPNTMMSPKKDFLYVLSQRKITKLRIEHCSVYTNCSACLESRD
PFCGWCSLEKRCTVRSTCQRDTSASRWLSLGSGQQCIEFESIIPEKIPIS
ELSHLHLIIRTLPEPFNAKYRCVFGNSTPIDAEILENGLGCATPPLDERP
LIPTNTDHILVPLSVRSSETNKDFVSRNFAFFDCSHHGNCQECLQSSWGC
NWCIFDNKCVHKSLQCRNIENAVSTVGHCPHLKKNRPEILLPVRVPIEIR
LEIENLPKPKSAHAGFLCTIHIEAAQMLLPAHVESNKIVVCEKTPYFYEI
NTHEYQAKVVVTWNFQHYVDTAIVTLYKCDVLGSHREHPDCSLCVTRDPK
YKCAWCSNSCVYNETCIADKNSISSGSKSAIENECPLPRIDIIKPLSGPV
EGGTLITIEGSNLGIREEDVRGKIFIGSVPCELENYQISVKIECRTGASL
YEMSAPIKVANDAGFTESSVQFHFKNVLLTGLYPTIGPRSGGTQLSLIGK
FLNIGSTMRAFLDEYECHIDVTQASSSQVSCTTSEATQPEPIRSLHLVID
GANRTLECQISTPSITNTNPTRSNFGSYQLRSLPRQPCSIFNYTQDPRIM
QIKPLRSFKSGGRVLTVHGIYLNSIQKPELEVFYDNERVNKTSCVVINSN
QMECPSPPVNYKFETFKKTNRKMDTELHLQNSSFQTETRYKNEYDRKKRR
ADFGDTFRLYTNAGSSANYFVNNNMDVTTFVKVHETQLNLQLSFVMDNVQ
LVRNLNKYFHDIRSTIVYLADPKYLPFPNDGVKLYKGDSLVIEGELLNLA
ADEYDVNVTIGTSQCNITSLALNQLLCIPPEQQPLPTDENGVDQSTDLPL
VVVKVGRNLRFVIGYLKYDLNKPYVFSHALLVGILTVALLVVVFVIVLII
FRRKSTQAEREYKRIQIQMITLESNVRSECKQAFAELQTDMTDLTADLES
TGIPTLDHVNYIMKVFFPGVSDHPILNSPKFREGSPQTNYDAAMVQFEQL
IGNKYFLLMFIETLEAQRSSFSIRDRVNVASLIMVVLMNKMEYATEILKS
LLLRLIDKSLASKHPQLMLRRTESVVEKMLTNYLAICMYDYLKEYAGSNL
FLLFKAIKHQIEKGLVDAITNDARYSLSEERLLHEQVTHSVVILHILQDD
LDEKVQCRVNDWDTISQVKLKILDAIFKNTPFSMRPSVNEVDLEWRHGRG
GHLTLQDEDLTTKTVNGWKRLNTLAHYGVKESAVMSLIARQNDNYHIPYS
KNQNSAPYHNFYFINNSQSHIIINNDIESGLQQPRVYHLVKPNIPDHYMN
IKNSVLSGGSPAFQSHVVNNCNDRVNKTIPEVYLTRLLATKGTIQKFVDD
FFSIILTVNEELPPAVKWLFDLLDEAARRHDIADTDIVHAWKSNCLPLRF
WVNFIKNPDFIFDVNKTYSVDSCLSVIAQTFMDACSTSEHRLGKDSPSNK
LLFAKDIPNYRIMVKEFYRDVSRLPQISDQEMSTAMQQLSVRQNEEFDTI
SALKELYIYITKYKDQIMESLETDINCRKMHLSRKLGNVAATLDGDCTSN
C

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website