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Signal Peptide Database - Mammalia
Entry Details
ID
20
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q8K410 (Created: 2004-12-07 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
ADA32_MOUSE
Protein Name
ADAM 32
Gene
Adam32
Organism Scientific
Mus musculus
Organism Common
Mouse
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Euarchontoglires
Glires
Rodentia
Sciurognathi
Muroidea
Muridae
Murinae
Mus
Protein Length [aa]
750
Protein Mass [Da]
83612
Features
Type
Description
Status
Start
End
signal peptide
potential
1
18
chain
ADAM 32
173
750
disulfide bond
by similarity
292
375
disulfide bond
by similarity
334
359
disulfide bond
by similarity
336
341
disulfide bond
by similarity
450
471
disulfide bond
by similarity
628
638
disulfide bond
by similarity
632
644
disulfide bond
by similarity
646
655
transmembrane region
potential
686
706
topological domain
Extracellular
potential
173
685
topological domain
Cytoplasmic
potential
707
750
domain
Peptidase M12B
183
380
domain
Disintegrin
387
479
domain
EGF-like
624
656
modified residue
Phosphoserine
by similarity
19
19
glycosylation site
N-linked (GlcNAc...)
potential
122
122
glycosylation site
N-linked (GlcNAc...)
potential
358
358
glycosylation site
N-linked (GlcNAc...)
potential
465
465
glycosylation site
N-linked (GlcNAc...)
potential
566
566
glycosylation site
N-linked (GlcNAc...)
potential
567
567
splice variant
(in isoform 2)
0
0
splice variant
(in isoform 2)
0
0
propeptide
potential
19
172
compositionally biased region
Cys-rich
480
502
SP Length
18
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MLHTLLLLLLAELGALLA
Sequence
MLHTLLLLLLAELGALLA
SGPESQSSFLEIIFPEKIEDKTHSEEQISYII
PINKKQYTVHLQKRYFLTNRFMVYMYNQGSTSFHSPNIPAQCYYQGHIKG
YPNSVATLSTCSGLRGFLQFENVSYGIEPLQSAFTSQHIVYKLGNKEKEL
IFNKNSRNIEMPTNYGILINKK
PKSPFKNLFP
LYLEMSIVVDKALYDYLG
SDSNIVTNKIIEIISLINSVFAQLKVTIVLSSLELWSDKNKIPTVGEADE
LLHKFLEWKQAYLTLRPHDVAYLFIYNEYPNYMGATYPGKMCTAHYSAGI
TMYPKDMTLEAFSVILTQMLGLSLGISYDEPEKCYCSESICIMNPRAMQY
GGVKSFS
N
CSLNDFEHFKSNEGAKCLQNKP
QMQRTA
AAVCGNGKVEGDEI
CDCGSEAECGPDSCCEPNRCVLKAGRACDSKSPSSTCCKNCQFLPEKHQC
RPEKHLYCDIPEVC
N
GSSGNCPPDVTINN
GHVCKESGTICYNGDCPDLDR
VC
ESIYGAGSVNAPFACYEEIQGQNDRFGNCGKDNRNRYVFCGWRNLICG
RLICTYPTRMPYNPP
N
N
STASVIYAFVRDKVCITVDFGSSVKEDPLRVAN
GATCDLDRICLNGVCVESRFLRD
QSKTCSSKCHGNGVCNSHGVCHCNAGY
SPPNCQ
YPTTKRSASLWSGKHDLPMERASKNQEKK
WLLSLYIVLIILASV
FLIGTG
WKGLKQCGSKEEESMSSESKSEDSTYTYVSRSTSETSSMTSTSS
Original
MLHTLLLLLLAELGALLASGPESQSSFLEIIFPEKIEDKTHSEEQISYII
PINKKQYTVHLQKRYFLTNRFMVYMYNQGSTSFHSPNIPAQCYYQGHIKG
YPNSVATLSTCSGLRGFLQFENVSYGIEPLQSAFTSQHIVYKLGNKEKEL
IFNKNSRNIEMPTNYGILINKKPKSPFKNLFPLYLEMSIVVDKALYDYLG
SDSNIVTNKIIEIISLINSVFAQLKVTIVLSSLELWSDKNKIPTVGEADE
LLHKFLEWKQAYLTLRPHDVAYLFIYNEYPNYMGATYPGKMCTAHYSAGI
TMYPKDMTLEAFSVILTQMLGLSLGISYDEPEKCYCSESICIMNPRAMQY
GGVKSFSNCSLNDFEHFKSNEGAKCLQNKPQMQRTAAAVCGNGKVEGDEI
CDCGSEAECGPDSCCEPNRCVLKAGRACDSKSPSSTCCKNCQFLPEKHQC
RPEKHLYCDIPEVCNGSSGNCPPDVTINNGHVCKESGTICYNGDCPDLDR
VCESIYGAGSVNAPFACYEEIQGQNDRFGNCGKDNRNRYVFCGWRNLICG
RLICTYPTRMPYNPPNNSTASVIYAFVRDKVCITVDFGSSVKEDPLRVAN
GATCDLDRICLNGVCVESRFLRDQSKTCSSKCHGNGVCNSHGVCHCNAGY
SPPNCQYPTTKRSASLWSGKHDLPMERASKNQEKKWLLSLYIVLIILASV
FLIGTGWKGLKQCGSKEEESMSSESKSEDSTYTYVSRSTSETSSMTSTSS
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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