Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q28483 (Created: 2008-09-02 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ADAM5_MACFA

Protein Name

Disintegrin and metalloproteinase domain-containing protein 5

Gene

ADAM5

Organism Scientific

Macaca fascicularis

Organism Common

Crab eating macaque

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Cercopithecidae
                          Cercopithecinae
                            Macaca

Protein Length [aa]

756

Protein Mass [Da]

85043

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   16
chain   Disintegrin and metalloproteinase domain- containing protein 5      143   756
disulfide bond      by similarity   292   375
disulfide bond      by similarity   334   359
disulfide bond      by similarity   336   341
disulfide bond      by similarity   449   470
disulfide bond      by similarity   634   646
disulfide bond      by similarity   640   652
disulfide bond      by similarity   654   663
transmembrane region      potential   699   719
topological domain   Extracellular   potential   17   698
topological domain   Cytoplasmic   potential   720   756
domain   Peptidase M12B      183   380
domain   Disintegrin      389   478
domain   EGF-like      630   664
glycosylation site   N-linked (GlcNAc...)   potential   559   559
propeptide      potential   17   142
compositionally biased region   Ser-rich      734   755

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MFLLLVLLTGLGGMHA

Sequence

MFLLLVLLTGLGGMHADLNPHKTFLQTTIPEKISSSDAKTDPEHNVVYMI
TIEGKPYFVHLKKQSILSSASFIHSYDKNDIRHSKPLLVQMDCNYNGYVA
GIPNSLVTLSVCSGLRGTMQLKNISYGIEPMEAVSGFIHKIYEEKFADTN
ILLEENDTYSWFNSEYQVRKSSEKTDFIKLFPRYIEMHIVVDKNLFDYMG
SDINAVTQKVIQIIGLVNTMLTQLQLTVIISSIEIWSNKNKISTTGHAEY
VLLEFFEWKKDHLNFKPHQIAYLFVYRKLPTLIGATFPGQVCNKDFAAAV
ALYPEGLSLESYTVIIVQLLGLNLGLTYDKTDTCHCSGDVCTMTPKAVYS
GGVKDFSVCSLDDFKYISSHNGLTCLQTNPLEMPTYTQRRICGNGLLEGG
EECDCGNKDNCTHKLCCDALTCRLKDNAQCGSGDCCSKDCKFKPANTICR
KSVDVECDFTEFCNGSYPYCLLDTYVRDGEYCDSGGAFCFQGRCRTFDKQ
CDDLIGRGSRGAPIFCYDEINTRGDKFGNCGTEYCLFQHILCGKLVCTWE
HKDLISRPNLSVIYAHVRDQTCVSTYLPSRKPPPVASTVSKTSYYSVDDR
DETFVQDGSVCGPDMYCFKMRCKHVRFLMDFETCEASIECSGHGICNNFN
HCHCEKGYNPPHCKPKKEAFGSTDDGHLVPAEKSYMEEGRHAPFQKQRFQ
LIFYISLPVLIITTAILIKRKKLRELCYRGETESESSVSQESSSNSKSSL
SESTSL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website