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Signal Peptide Database - Viruses
Entry Details
ID
266
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P51519 (Created: 1996-10-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
ENV_BLV
Protein Name
Envelope glycoprotein
Gene
env
Organism Scientific
Bovine leukemia virus
Organism Common
BLV
Lineage
Viruses
Retro-transcribing viruses
Retroviridae
Orthoretrovirinae
Deltaretrovirus
Protein Length [aa]
515
Protein Mass [Da]
58640
Features
Type
Description
Status
Start
End
signal peptide
potential
1
33
chain
Envelope glycoprotein
34
515
chain
Surface protein
by similarity
34
301
chain
Transmembrane protein
by similarity
302
515
disulfide bond
Alternate
by similarity
212
215
disulfide bond
Interchain (between SU and TM chains, or C-215 with C-392); alternate
by similarity
212
392
disulfide bond
by similarity
384
391
transmembrane region
potential
437
457
topological domain
Extracellular
potential
1
436
topological domain
Cytoplasmic
potential
458
515
region of interest
Fusion peptide
potential
304
324
region of interest
Immunosuppression
by similarity
365
381
glycosylation site
N-linked (GlcNAc...)
potential
129
129
glycosylation site
N-linked (GlcNAc...)
potential
203
203
glycosylation site
N-linked (GlcNAc...)
potential
230
230
glycosylation site
N-linked (GlcNAc...)
potential
251
251
glycosylation site
N-linked (GlcNAc...)
potential
256
256
glycosylation site
N-linked (GlcNAc...)
potential
271
271
glycosylation site
N-linked (GlcNAc...)
potential
287
287
glycosylation site
N-linked (GlcNAc...)
potential
351
351
glycosylation site
N-linked (GlcNAc...)
potential
398
398
site
Cleavage; by host
by similarity
301
302
short sequence motif
CXXC
212
215
short sequence motif
CX6CC
384
392
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
455
455
coiled-coil region
potential
330
376
coiled-coil region
potential
388
420
SP Length
33
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MPKERRSRRRPQPIIRWVSLTLTLLALCQPIQT
Sequence
MPKERRSRRRPQPIIRWVSLTLTLLALCQPIQTWRCSLSLGNQQWMTTYN
QEAKFSISIDQILEAHNQSPFCPRSPRYTLDFVNGYPKIYWPPPQGRRRF
GARAMVTYDCEPRCPYVGADHFDCPHWD
N
ASQADQGSFYVNHQILFLHLK
QCHGIFTLTWEIWGYDPLITFSLHKIPDPPQPDFPQLNSDWVPSVRSWAL
LL
N
QTARAFPD
CAIC
WEPSPPWAPEILVY
N
KTISGSGPGLALPDAQIFWV
N
TSLF
N
TTQGWHHPSQRLLF
N
VSQGNALLLPPISLV
N
LSTVSSAPPTRVR
RS
P
VAALTLGLALSVGLTGINVAV
SALSH
QRLTSLIHVLEQDQQRLITAI
NQTHYNLLNVASVVAQNRRGLDWLYI
RLGFQ
SL
CPTI
NEPCCFLRIQNDS
IIRLGDLQPLSQRVSTDWQW
PWNWDLGLTAWVRETI
HSVLSLFLLALFLL
FLAP
C
LI
KCLTSRLLKLLRQAPHFPEISFPPKPDSDYQALLPSAPEIYSH
LSPTKPDYINLRPCP
Original
MPKERRSRRRPQPIIRWVSLTLTLLALCQPIQTWRCSLSLGNQQWMTTYN
QEAKFSISIDQILEAHNQSPFCPRSPRYTLDFVNGYPKIYWPPPQGRRRF
GARAMVTYDCEPRCPYVGADHFDCPHWDNASQADQGSFYVNHQILFLHLK
QCHGIFTLTWEIWGYDPLITFSLHKIPDPPQPDFPQLNSDWVPSVRSWAL
LLNQTARAFPDCAICWEPSPPWAPEILVYNKTISGSGPGLALPDAQIFWV
NTSLFNTTQGWHHPSQRLLFNVSQGNALLLPPISLVNLSTVSSAPPTRVR
RSPVAALTLGLALSVGLTGINVAVSALSHQRLTSLIHVLEQDQQRLITAI
NQTHYNLLNVASVVAQNRRGLDWLYIRLGFQSLCPTINEPCCFLRIQNDS
IIRLGDLQPLSQRVSTDWQWPWNWDLGLTAWVRETIHSVLSLFLLALFLL
FLAPCLIKCLTSRLLKLLRQAPHFPEISFPPKPDSDYQALLPSAPEIYSH
LSPTKPDYINLRPCP
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11