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Signal Peptide Database - Viruses
Entry Details
ID
392
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q6DQ15 (Created: 2007-11-13 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
HEMA_I02A7
Protein Name
Hemagglutinin
Gene
HA
Organism Scientific
Influenza A virus (strain A/Teal/China/2978.1/2002 H5N1 genotype W)
Organism Common
Lineage
Viruses
ssRNA negative-strand viruses
Orthomyxoviridae
Influenzavirus A
Protein Length [aa]
545
Protein Mass [Da]
61731
Features
Type
Description
Status
Start
End
signal peptide
1
12
chain
Hemagglutinin HA1 chain
13
334
chain
Hemagglutinin HA2 chain
343
545
disulfide bond
Interchain (between HA1 and HA2 chains)
by similarity
16
479
disulfide bond
by similarity
54
286
disulfide bond
by similarity
67
79
disulfide bond
by similarity
102
147
disulfide bond
by similarity
290
314
disulfide bond
by similarity
486
490
topological domain
Extracellular
potential
13
545
glycosylation site
N-linked (GlcNAc...)
potential
22
22
glycosylation site
N-linked (GlcNAc...)
potential
23
23
glycosylation site
N-linked (GlcNAc...)
potential
35
35
glycosylation site
N-linked (GlcNAc...)
potential
177
177
glycosylation site
N-linked (GlcNAc...)
potential
298
298
glycosylation site
N-linked (GlcNAc...)
potential
496
496
site
Cleavage; by host
by similarity
342
343
propeptide
Connecting peptide
335
342
non-terminal residue
1
1
non-terminal residue
545
545
SP Length
12
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
VLLLAIVSLVKS
Sequence
V
LLLAIVSLVKS
DQICIGYHA
N
N
STEQVDTIMEK
N
VTVTHAQDILEKTHN
GKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVERASPAND
LCYPGDFNDYEELKHLLSRINHFEKIQIFPKSSWPNHEASSGVSSACPYQ
GRSSFFRNVVWLIKKNSAYPTIKRSY
N
NTNQEDLLVLWGIHHPNDAAEQT
KLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDA
INFESNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAI
N
SS
MPFHNIHPLTIGECPKYVKSNRLVLATGLRNSPQ
REIRRKKR
G
LFGAIAG
FIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDK
MNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTL
DFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVK
N
GTYD
YPHYSEEARLNREEISGVKLESIGTYQILSIYSTVASSLALAIM
V
Original
VLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHN
GKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVERASPAND
LCYPGDFNDYEELKHLLSRINHFEKIQIFPKSSWPNHEASSGVSSACPYQ
GRSSFFRNVVWLIKKNSAYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQT
KLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDA
INFESNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSS
MPFHNIHPLTIGECPKYVKSNRLVLATGLRNSPQREIRRKKRGLFGAIAG
FIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDK
MNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTL
DFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVKNGTYD
YPHYSEEARLNREEISGVKLESIGTYQILSIYSTVASSLALAIMV
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11