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Signal Peptide Database - Viruses
Entry Details
ID
393
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P16060 (Created: 1990-04-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
HEMA_I66A0
Protein Name
Hemagglutinin
Gene
HA
Organism Scientific
Influenza A virus (strain A/Turkey/Ontario/7732/1966 H5N9)
Organism Common
Lineage
Viruses
ssRNA negative-strand viruses
Orthomyxoviridae
Influenzavirus A
Protein Length [aa]
565
Protein Mass [Da]
63963
Features
Type
Description
Status
Start
End
signal peptide
1
16
chain
Hemagglutinin HA1 chain
17
342
chain
Hemagglutinin HA2 chain
344
565
disulfide bond
Interchain (between HA1 and HA2 chains)
by similarity
20
480
disulfide bond
by similarity
58
290
disulfide bond
by similarity
71
83
disulfide bond
by similarity
106
151
disulfide bond
by similarity
294
318
disulfide bond
by similarity
487
491
transmembrane region
potential
529
549
topological domain
Extracellular
potential
17
528
topological domain
Cytoplasmic
potential
550
565
glycosylation site
N-linked (GlcNAc...)
potential
26
26
glycosylation site
N-linked (GlcNAc...)
potential
27
27
glycosylation site
N-linked (GlcNAc...)
potential
39
39
glycosylation site
N-linked (GlcNAc...)
potential
142
142
glycosylation site
N-linked (GlcNAc...)
potential
170
170
glycosylation site
N-linked (GlcNAc...)
potential
181
181
glycosylation site
N-linked (GlcNAc...)
potential
302
302
glycosylation site
N-linked (GlcNAc...)
potential
497
497
site
Cleavage; by host
by similarity
343
344
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
554
554
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
561
561
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
564
564
SP Length
16
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MERIVIALAIISVVKG
Sequence
MERIVIALAIISVVKG
DQICIGYHA
N
N
STKQVDTIMEK
N
VTVTYAQDILE
KEHNGKLCSLKGVRPLILKDCSVAGWLLGNPMCDEFLNVPEWSYIVEKDN
PTNGLCYPGDFNDYEELKHLMSSTNHIEKIRIIPRNSWSEH
N
ASSGVSSS
CPYNGRSSFYRNVVWLIKK
N
NSYPTIKRTY
N
NTNVEDLLILWGIHHPADA
AEQTRLYKNSNTYVSVGTSTLNQRSIPEIATRPKVNGQNGRIEFFWTILR
PNHAISFESNGNFIAPEYAYKIVKKGDSAIMRSELEYGNCDTKCQTPVGA
I
N
SSMPFHNVHPLTIGECPKYVKSNKLVLATGPRNVPQRRKK
RG
LFGAKA
GFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTHKAIDGITNKVNSIID
KMNTQFEAVGKEFNNLERRIENLNKQMEDGFLDVWTYNAELLVLMENERT
LDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVR
N
GTY
DYPQYSEESRLNREEIDGVKLESMGTYQ
ILSIYSTVASSLALAIMVAGL
S
FWM
C
SNGSLQ
C
RI
C
I
Original
MERIVIALAIISVVKGDQICIGYHANNSTKQVDTIMEKNVTVTYAQDILE
KEHNGKLCSLKGVRPLILKDCSVAGWLLGNPMCDEFLNVPEWSYIVEKDN
PTNGLCYPGDFNDYEELKHLMSSTNHIEKIRIIPRNSWSEHNASSGVSSS
CPYNGRSSFYRNVVWLIKKNNSYPTIKRTYNNTNVEDLLILWGIHHPADA
AEQTRLYKNSNTYVSVGTSTLNQRSIPEIATRPKVNGQNGRIEFFWTILR
PNHAISFESNGNFIAPEYAYKIVKKGDSAIMRSELEYGNCDTKCQTPVGA
INSSMPFHNVHPLTIGECPKYVKSNKLVLATGPRNVPQRRKKRGLFGAKA
GFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTHKAIDGITNKVNSIID
KMNTQFEAVGKEFNNLERRIENLNKQMEDGFLDVWTYNAELLVLMENERT
LDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTY
DYPQYSEESRLNREEIDGVKLESMGTYQILSIYSTVASSLALAIMVAGLS
FWMCSNGSLQCRICI
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
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, Dresden, Germany, last update 2010-06-11