Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

394

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P03446 (Created: 1986-07-21 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I76A2

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Duck/Alberta/60/1976 H12N5)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

564

Protein Mass [Da]

63713

Features

TypeDescriptionStatusStartEnd
signal peptide         1   17
chain   Hemagglutinin HA1 chain      18   341
chain   Hemagglutinin HA2 chain      343   564
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   21   479
disulfide bond      by similarity   59   290
disulfide bond      by similarity   72   84
disulfide bond      by similarity   107   150
disulfide bond      by similarity   294   318
disulfide bond      by similarity   486   490
transmembrane region      potential   531   551
topological domain   Extracellular   potential   17   530
topological domain   Cytoplasmic   potential   552   564
glycosylation site   N-linked (GlcNAc...)   potential   27   27
glycosylation site   N-linked (GlcNAc...)   potential   28   28
glycosylation site   N-linked (GlcNAc...)   potential   140   140
glycosylation site   N-linked (GlcNAc...)   potential   151   151
glycosylation site   N-linked (GlcNAc...)   potential   152   152
glycosylation site   N-linked (GlcNAc...)   potential   222   222
glycosylation site   N-linked (GlcNAc...)   potential   302   302
glycosylation site   N-linked (GlcNAc...)   potential   309   309
glycosylation site   N-linked (GlcNAc...)   potential   496   496
glycosylation site   N-linked (GlcNAc...)   potential   523   523
site   Cleavage; by host   by similarity   342   343
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   553   553
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   560   560
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   563   563

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MEKFIILSTVLAASFAY

Sequence

MEKFIILSTVLAASFAYDKICIGYQTNNSTETVNTLSEQNVPVTQVEELV
HRGIDPILCGTELGSPLVLDDCSLEGLILGNPKCDLYLNGREWSYIVERP
KEMEGVCYPGSIENQEELRSLFSSIKKYERVKMFDFTKWNVTYTGTSKAC
NNTSNQGSFYRSMRWLTLKSGQFPVQTDEYKNTRDSDIVFTWAIHHPPTS
DEQVKLYKNPDTLSSVTTVEINRSFKPNIGPRPLVRGQQGRMDYYWAVLK
PGQTVKIQTNGNLIAPEYGHLITGKSHGRILKNNLPMGQCVTECQLNEGV
MNTSKPFQNTSKHYIGKCPKYIPSGSLKLAIGLRNVPQVQDRGLFGAIAG
FIEGGWPGLVAGWYGFQHQNAEGTGIAADRDSTQRAIDNMQNKLNNVIDK
MNKQFEVVNHEFSEVESRINMINSKIDDQITDIWAYNAELLVLLENQKTL
DEHDANVRNLHDRVRRVLRENAIDTGDGCFEILHKCDNNCMDTIRNGTYN
HKEYEEESKIERQKVNGVKLEENSTYKILSIYSSVASSLVLLLMIIGGFI
FGCQNGNVRCTFCI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website