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Signal Peptide Database - Viruses
Entry Details
ID
395
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q6LEJ4 (Created: 2007-03-06 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
HEMA_I80A2
Protein Name
Hemagglutinin
Gene
HA
Organism Scientific
Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7)
Organism Common
Lineage
Viruses
ssRNA negative-strand viruses
Orthomyxoviridae
Influenzavirus A
Protein Length [aa]
560
Protein Mass [Da]
62168
Features
Type
Description
Status
Start
End
signal peptide
potential
1
18
chain
Hemagglutinin HA1 chain
19
338
chain
Hemagglutinin HA2 chain
340
560
disulfide bond
Interchain (between HA1 and HA2 chains)
by similarity
22
476
disulfide bond
by similarity
60
286
disulfide bond
by similarity
72
84
disulfide bond
by similarity
105
147
disulfide bond
by similarity
290
314
disulfide bond
by similarity
483
487
transmembrane region
potential
524
544
topological domain
Extracellular
potential
19
523
topological domain
Cytoplasmic
potential
545
560
glycosylation site
N-linked (GlcNAc...)
potential
30
30
glycosylation site
N-linked (GlcNAc...)
potential
46
46
glycosylation site
N-linked (GlcNAc...)
potential
141
141
glycosylation site
N-linked (GlcNAc...)
potential
249
249
glycosylation site
N-linked (GlcNAc...)
potential
421
421
glycosylation site
N-linked (GlcNAc...)
potential
493
493
sequence variant
(in strain: SC35M mouse- adapted)
0
0
sequence variant
(in strain: SC35M mouse-adapted)
0
0
sequence variant
(in strain: SC35M mouse-adapted)
0
0
sequence variant
(in strain: SC35M mouse-adapted)
0
0
site
Cleavage; by host
by similarity
339
340
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
548
548
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
556
556
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
559
559
SP Length
18
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MNTQILVFIACVLIEAKG
Sequence
MNTQILVFIACVLIEAKG
DKICLGHHAVA
N
GTKVNTLTERGIEVV
N
ATET
VETANIGKICTQGKRPTDLGQCGLLGTLIGPPQCDQFLEFESNLIIERRE
GNDVCYPGKFTNEESLRQILRGSGGVDKESMGFTYSGIRT
N
GTTSACRRS
GSSFYAEMKWLLSNSDNAAFPQMTKSYRNPRNKPALIVWGIHHSGSTTEQ
TRLYGSGNKLITVGSSKYQQSFTPSPGARPQVNGQSGRIDFHWLLLDP
N
D
TVTFTFNGAFIAPNRASFFRGESLGVQSDVPLDSNCGGDCFHSGGTIVSS
LPFQNINSRTVGKCPRYVKQPSLLLATGMRNVPENPKT
RG
LFGAIAGFIE
NGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIDKTNQ
QFELIDNEFNEIEQQIGNVI
N
WTRDSMTEVWSYNAELLVAMENQHTIDLA
DSEMNKLYERVRKQLRENAEEDGTGCFEIFHKCDDQCMESIR
N
NTYDHTQ
YRAKSLQNRIQIDPVKLSSGYKD
IILWFSFGASCFLLLAIAMGL
VFI
C
IK
NGNMR
C
TI
C
I
Original
MNTQILVFIACVLIEAKGDKICLGHHAVANGTKVNTLTERGIEVVNATET
VETANIGKICTQGKRPTDLGQCGLLGTLIGPPQCDQFLEFESNLIIERRE
GNDVCYPGKFTNEESLRQILRGSGGVDKESMGFTYSGIRTNGTTSACRRS
GSSFYAEMKWLLSNSDNAAFPQMTKSYRNPRNKPALIVWGIHHSGSTTEQ
TRLYGSGNKLITVGSSKYQQSFTPSPGARPQVNGQSGRIDFHWLLLDPND
TVTFTFNGAFIAPNRASFFRGESLGVQSDVPLDSNCGGDCFHSGGTIVSS
LPFQNINSRTVGKCPRYVKQPSLLLATGMRNVPENPKTRGLFGAIAGFIE
NGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIDKTNQ
QFELIDNEFNEIEQQIGNVINWTRDSMTEVWSYNAELLVAMENQHTIDLA
DSEMNKLYERVRKQLRENAEEDGTGCFEIFHKCDDQCMESIRNNTYDHTQ
YRAKSLQNRIQIDPVKLSSGYKDIILWFSFGASCFLLLAIAMGLVFICIK
NGNMRCTICI
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11