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Signal Peptide Database - Viruses
Entry Details
ID
396
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P09344 (Created: 1989-07-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
HEMA_I85A6
Protein Name
Hemagglutinin
Gene
HA
Organism Scientific
Influenza A virus (strain A/Starling/Victoria/5156/1985 H7N7)
Organism Common
Lineage
Viruses
ssRNA negative-strand viruses
Orthomyxoviridae
Influenzavirus A
Protein Length [aa]
563
Protein Mass [Da]
62730
Features
Type
Description
Status
Start
End
signal peptide
1
18
chain
Hemagglutinin HA1 chain
19
335
chain
Hemagglutinin HA2 chain
343
563
disulfide bond
Interchain (between HA1 and HA2 chains)
by similarity
22
479
disulfide bond
by similarity
60
286
disulfide bond
by similarity
72
84
disulfide bond
by similarity
105
147
disulfide bond
by similarity
290
314
disulfide bond
by similarity
486
490
transmembrane region
potential
527
547
topological domain
Extracellular
potential
19
526
topological domain
Cytoplasmic
potential
548
563
glycosylation site
N-linked (GlcNAc...)
potential
30
30
glycosylation site
N-linked (GlcNAc...)
potential
46
46
glycosylation site
N-linked (GlcNAc...)
potential
249
249
glycosylation site
N-linked (GlcNAc...)
potential
424
424
glycosylation site
N-linked (GlcNAc...)
potential
496
496
site
Cleavage; by host
by similarity
342
343
propeptide
Connecting peptide
336
342
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
551
551
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
559
559
lipid moiety-binding region
S-palmitoyl cysteine; by host
by similarity
562
562
SP Length
18
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MNTQILILTLVAAIHTNA
Sequence
MNTQILILTLVAAIHTNA
DKICLGHHAVS
N
GTKVNTLTERGVEVV
N
ATET
VERRTIPRICTKGKKAIDLGQCGLLGIITGPPQCDQFLEFTADLIIERRE
GNDVCYPGKFVNEEALRQILRESGGINKETTGFTYSGIRTNGVTSACRRS
GSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRNEPALIVWGIHHSGSATEQ
TKLYGSGNKLITVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLILNP
N
D
TVTFSFNGAFVAPDRVSFFKGKSMGIQSEVPVDTNCEGECYHNGGTITSN
LPFQNVNSRAVGKCPRYVKQKSLLLATGMKNVPEI
PKKREKR
G
LFGAIAG
FIENGWEGLVDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEK
TNQQFELIDNEFTEVEKQIGNVI
N
WTRDSITEVWSYNADLLVAMENQHTI
DLTDSEMNKLYERVRRQLRENAEEDCTGCFEIFHKCDDDCMASIR
N
NTYD
HSTYREEAMQNRVKIDPVKLSSGYKD
VILWFSLGASCFLLLAIAMGL
VFM
C
VKNGNMR
C
TI
C
I
Original
MNTQILILTLVAAIHTNADKICLGHHAVSNGTKVNTLTERGVEVVNATET
VERRTIPRICTKGKKAIDLGQCGLLGIITGPPQCDQFLEFTADLIIERRE
GNDVCYPGKFVNEEALRQILRESGGINKETTGFTYSGIRTNGVTSACRRS
GSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRNEPALIVWGIHHSGSATEQ
TKLYGSGNKLITVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLILNPND
TVTFSFNGAFVAPDRVSFFKGKSMGIQSEVPVDTNCEGECYHNGGTITSN
LPFQNVNSRAVGKCPRYVKQKSLLLATGMKNVPEIPKKREKRGLFGAIAG
FIENGWEGLVDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEK
TNQQFELIDNEFTEVEKQIGNVINWTRDSITEVWSYNADLLVAMENQHTI
DLTDSEMNKLYERVRRQLRENAEEDCTGCFEIFHKCDDDCMASIRNNTYD
HSTYREEAMQNRVKIDPVKLSSGYKDVILWFSLGASCFLLLAIAMGLVFM
CVKNGNMRCTICI
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11