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Signal Peptide Database - Drosophila melanogaster
Entry Details
ID
413
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q08180 (Created: 1995-02-01 Updated: 2008-12-16)
UniProtKB/Swiss-Prot Entry Name
ICCR_DROME
Protein Name
Irregular chiasm C-roughest protein
Gene
rst
Organism Scientific
Drosophila melanogaster
Organism Common
Fruit fly
Lineage
Eukaryota
Metazoa
Arthropoda
Hexapoda
Insecta
Pterygota
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Ephydroidea
Drosophilidae
Drosophila
Sophophora
Protein Length [aa]
764
Protein Mass [Da]
83005
Features
Type
Description
Status
Start
End
signal peptide
potential
1
19
chain
Irregular chiasm C-roughest protein
20
764
disulfide bond
by similarity
49
107
disulfide bond
by similarity
155
214
disulfide bond
by similarity
281
325
disulfide bond
by similarity
367
408
disulfide bond
by similarity
450
508
transmembrane region
potential
534
556
topological domain
Extracellular
potential
20
533
topological domain
Cytoplasmic
potential
557
764
domain
Ig-like C2-type 1
21
120
domain
Ig-like C2-type 2
132
230
domain
Ig-like C2-type 3
237
343
domain
Ig-like C2-type 4
346
419
domain
Ig-like C2-type 5
430
530
glycosylation site
N-linked (GlcNAc...)
potential
211
211
glycosylation site
N-linked (GlcNAc...)
potential
313
313
glycosylation site
N-linked (GlcNAc...)
potential
393
393
glycosylation site
N-linked (GlcNAc...)
potential
400
400
glycosylation site
N-linked (GlcNAc...)
potential
507
507
compositionally biased region
Gly-rich
245
261
compositionally biased region
Gln-rich (OPA repeat)
637
660
compositionally biased region
Poly-Thr
721
725
SP Length
19
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MLHTMQLLLLATIVGMVRS
Sequence
MLHTMQLLLLATIVGMVRS
S
PYTSYQNQRFAMEPQDQTAVVGARVTLPCR
VINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLD
DDARYQCQVSPGPEGQPAIR
STFAGLTVLVP
PEAPKITQGDVIYATEDRK
VEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLR
LTPKKEHHNT
N
FSCQAQNTADRTYRSAKIR
VEVKYA
PKVKVNVM
GSLPGG
AGGSVGGAGGG
SVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEP
IIGGQKTEMVIR
N
VTRKFHDAIVKCEVQNSVGKSEDSETLDIS
YA
PSFRQ
RPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTST
N
LTFSVS
N
ETAGRYYCKANVPGYAEIS
ADAYVYLKGS
PAIGSQRTQYGLVGDTARIEC
FASSVPRARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQA
YHYGKY
N
CTVVNDYGNDVAEIQLQAKKSVS
LLM
TIVGGISVVAFLLVLTI
LVVVYI
KCKKRTKLPPADVISEHQITKNGGVSCKLEPGDRTSNYSDLKVD
ISGGYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIM
QNNHQNQLQLQQQQ
QQSHHQHHTQ
TTTLPMTFLTNSSGGSLTGSIIGSREIRQDNGLPSLQSTT
ASVVSSSPNGSCSNQSTTAA
TTTTT
HVVVPSSMALSVDPRYSAIYGNPYL
RSSNSSLLPPPTAV
Original
MLHTMQLLLLATIVGMVRSSPYTSYQNQRFAMEPQDQTAVVGARVTLPCR
VINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLD
DDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRK
VEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLR
LTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGG
AGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEP
IIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQ
RPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFSVSN
ETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIEC
FASSVPRARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQA
YHYGKYNCTVVNDYGNDVAEIQLQAKKSVSLLMTIVGGISVVAFLLVLTI
LVVVYIKCKKRTKLPPADVISEHQITKNGGVSCKLEPGDRTSNYSDLKVD
ISGGYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQ
QQSHHQHHTQTTTLPMTFLTNSSGGSLTGSIIGSREIRQDNGLPSLQSTT
ASVVSSSPNGSCSNQSTTAATTTTTHVVVPSSMALSVDPRYSAIYGNPYL
RSSNSSLLPPPTAV
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11