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Signal Peptide Database - Drosophila melanogaster
Entry Details
ID
444
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q24247 (Created: 1997-11-01 Updated: 2008-12-16)
UniProtKB/Swiss-Prot Entry Name
ITA1_DROME
Protein Name
Integrin alpha-PS1
Gene
mew
Organism Scientific
Drosophila melanogaster
Organism Common
Fruit fly
Lineage
Eukaryota
Metazoa
Arthropoda
Hexapoda
Insecta
Pterygota
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Ephydroidea
Drosophilidae
Drosophila
Sophophora
Protein Length [aa]
1146
Protein Mass [Da]
127973
Features
Type
Description
Status
Start
End
signal peptide
potential
1
30
chain
Integrin alpha-PS1
31
1146
chain
Integrin alpha-PS1 heavy chain
potential
31
960
chain
Integrin alpha-PS1 light chain
potential
961
1146
transmembrane region
potential
1086
1106
topological domain
Extracellular
potential
31
1085
topological domain
Cytoplasmic
potential
1107
1146
glycosylation site
N-linked (GlcNAc...)
potential
68
68
glycosylation site
N-linked (GlcNAc...)
potential
86
86
glycosylation site
N-linked (GlcNAc...)
potential
147
147
glycosylation site
N-linked (GlcNAc...)
potential
470
470
glycosylation site
N-linked (GlcNAc...)
potential
511
511
glycosylation site
N-linked (GlcNAc...)
657
657
glycosylation site
N-linked (GlcNAc...)
potential
680
680
glycosylation site
N-linked (GlcNAc...)
potential
711
711
glycosylation site
N-linked (GlcNAc...)
potential
718
718
glycosylation site
N-linked (GlcNAc...)
potential
761
761
glycosylation site
N-linked (GlcNAc...)
potential
928
928
glycosylation site
N-linked (GlcNAc...)
1027
1027
repeat
FG-GAP 1
49
116
repeat
FG-GAP 2
117
0
repeat
FG-GAP 3
199
263
repeat
FG-GAP 4
264
317
repeat
FG-GAP 5
318
374
repeat
FG-GAP 6
377
434
repeat
FG-GAP 7
443
497
splice variant
(in isoform A)
1
97
SP Length
30
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MLELPFTTIRPNCRLRQNLGILIILQCVLT
Sequence
MLELPFTTIRPNCRLRQNLGILIILQCVLTCYNFNLEQRLPIVKYGHPHS
HFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCP
MTQ
RFDDCEQVITDGRRNF
DSEILSPPGNDEIKEDQWMGVTVRSNPLQA
N
GSG
GKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEVHEPCKGRPVQRQ
HE
DYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTY
YSDHSDLNSPVDK
YSYLGMSVTGGRFFGHMSYAAGAPRSEGHGQVVIFDK
STDNPIPVHSILDGEQF
GSSFGYELATADINGDHRPDLIVAAPLYFTKTE
GGAVYVYQNIQDTLPMKYTLKLTG
PL
ESRFGLALANIGDLNKDNCEDLAV
GAPYEGNGVVYIYLGSSQGLNSKPAQKIQASELG
GTIPNGQP
IRTFGISI
SGNTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNM
DPN
TPGCLDDPAS
N
LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKF
SRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKANTRDIQTPVRF
RLKYSLVEPPLADSALVRLNPILDQTQAHVDFEGTFQKDCGDDDLCESNL
IIRVEP
N
ITESSGNEYTLILDETELEVRI
N
VSNLADSAYEAQLFIAHQAG
VSYVATKKPT
N
ATCNSY
N
TTLVACSLGNPMLRDTTTFVTIRFQPKGLEPS
EKIMLFHIFA
N
TTSKLVGPERPERDLRVNVVRRAKLNFRGWAIPEQSFYS
GSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPSTAPKVQM
VIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLA
SGSRENPAYLSAPAQMRMFPSQSRHSF
N
KSLIHSQRSYYSSSHRDDHSDD
TQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQDIVELDCNKGATN
CVRIECDILNMPALSEAQVVVKARLW
N
STLVSEYPRVERVRIFSTATAQI
PESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPW
LIIILGIVGGLLLLA
LVTYVL
WKVGFFKRIRPTDPTLSGNLEKMNEEKPFLAPSKNTHHVF
Original
MLELPFTTIRPNCRLRQNLGILIILQCVLTCYNFNLEQRLPIVKYGHPHS
HFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQ
RFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSG
GKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEVHEPCKGRPVQRQHE
DYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTY
YSDHSDLNSPVDKYSYLGMSVTGGRFFGHMSYAAGAPRSEGHGQVVIFDK
STDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTE
GGAVYVYQNIQDTLPMKYTLKLTGPLESRFGLALANIGDLNKDNCEDLAV
GAPYEGNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISI
SGNTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPN
TPGCLDDPASNLTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKF
SRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKANTRDIQTPVRF
RLKYSLVEPPLADSALVRLNPILDQTQAHVDFEGTFQKDCGDDDLCESNL
IIRVEPNITESSGNEYTLILDETELEVRINVSNLADSAYEAQLFIAHQAG
VSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPS
EKIMLFHIFANTTSKLVGPERPERDLRVNVVRRAKLNFRGWAIPEQSFYS
GSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPSTAPKVQM
VIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLA
SGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDD
TQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQDIVELDCNKGATN
CVRIECDILNMPALSEAQVVVKARLWNSTLVSEYPRVERVRIFSTATAQI
PESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPWLIIILGIVGGLLLLA
LVTYVLWKVGFFKRIRPTDPTLSGNLEKMNEEKPFLAPSKNTHHVF
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11