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Signal Peptide Database - Mammalia
Entry Details
ID
49
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q29437 (Created: 1997-11-01 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
AOCX_BOVIN
Protein Name
Primary amine oxidase, liver isozyme
Gene
Organism Scientific
Bos taurus
Organism Common
Bovine
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Laurasiatheria
Cetartiodactyla
Ruminantia
Pecora
Bovidae
Bovinae
Bos
Protein Length [aa]
762
Protein Mass [Da]
84757
Features
Type
Description
Status
Start
End
signal peptide
1
16
chain
Primary amine oxidase, liver isozyme
17
762
modified residue
2',4',5'-topaquinone
470
470
glycosylation site
N-linked (GlcNAc...)
136
136
glycosylation site
N-linked (GlcNAc...)
231
231
glycosylation site
N-linked (GlcNAc...)
665
665
strand
92
101
strand
122
129
strand
131
134
strand
136
147
strand
150
153
strand
207
210
strand
216
218
strand
223
230
strand
241
249
strand
252
254
strand
259
265
strand
268
271
strand
323
325
strand
328
330
strand
332
341
strand
345
353
strand
356
371
strand
382
384
strand
407
417
strand
422
434
strand
457
467
strand
470
478
strand
484
492
strand
507
511
strand
514
517
strand
519
529
strand
533
550
strand
553
568
strand
575
577
strand
585
593
strand
599
607
strand
629
635
strand
669
683
strand
700
712
helix
64
77
helix
85
87
helix
105
114
helix
155
159
helix
165
167
helix
172
184
helix
187
190
helix
191
198
helix
255
257
helix
273
281
helix
376
380
helix
385
387
helix
503
506
helix
571
574
helix
621
628
helix
659
662
helix
687
689
active site
Proton acceptor
by similarity
385
385
active site
Schiff-base intermediate with substrate; via topaquinone
by similarity
470
470
metal ion-binding site
Copper
519
519
metal ion-binding site
Copper
521
521
metal ion-binding site
Calcium 1
528
528
metal ion-binding site
Calcium 1; via carbonyl oxygen
529
529
metal ion-binding site
Calcium 1
530
530
metal ion-binding site
Calcium 2
571
571
metal ion-binding site
Calcium 2
by similarity
637
637
metal ion-binding site
Calcium 2; via carbonyl oxygen
662
662
metal ion-binding site
Calcium 2
664
664
metal ion-binding site
Calcium 2
666
666
metal ion-binding site
Calcium 1
672
672
metal ion-binding site
Calcium 1; via carbonyl oxygen
673
673
metal ion-binding site
Copper
683
683
turn
200
203
turn
342
344
turn
390
393
turn
399
401
turn
646
650
SP Length
16
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MFIFIFLSLWTLLVMG
Sequence
MFIFIFLSLWTLLVMG
REEGGVGSEEGVGKQCHPSLPPRCPSRSPSDQPW
THPDQSQLFADLS
REELTTVMSFLTQQ
LGPDLVD
AAQ
ARPS
DNCVFSVEL
Q
LPP
KAAALAHLDR
GSPPPAR
EALAIVFF
G
GQPQ
P
NVTELVVGPLPQ
PS
Y
MRD
V
TVERH
GGPLP
YYR
RPVL
LREYLDIDQMIFN
RE
LPQA
AGVLHHCC
S
Y
KQG
GQK
LLTM
NSAPR
GVQ
SGDR
STWFGIYY
N
ITKGGPYLH
PVGLELLVD
H
K
ALD
PAD
W
TVQKVFF
QG
RYYE
N
LAQLEEQFE
AGQVNVVVIPDDGTGGFWS
LKSQVPPGPTPPLQFHPQGPRF
SVQ
GN
RVA
S
SLWTFSFGLG
AFS
GPRVFD
VRF
QG
ERLAYEISLQEAGAVY
GGNT
PAAML
T
RYM
D
SG
FG
MGYF
ATPLI
RG
V
DCPYL
ATYMDWHFVVE
SQTP
KTLHDAFCVFEQN
KGLPLRRHHSDFLSHY
FGGVAQ
TVLVFRSVSTM
LN
Y
DYVWDMVF
YPNGA
IEVKLHATG
YISSAFLF
GA
ARRY
GNQVG
EH
TLGP
V
H
T
H
SAHYKV
D
L
D
VG
GLENWVWAEDMAFVPTAI
PW
SPEHQIQRLQVTRKQL
ET
E
EQA
AFP
LGGASPR
YLYLASKQS
NKWGH
PR
GYRIQTV
SFAGGPMPQNSPM
ERAFSWGR
YQLAITQ
R
K
ETEPSSSS
VFNQN
DPWTPTVD
FSD
F
I
N
N
E
TI
AGK
D
L
VAWVTAGFL
H
IPH
AED
IPNTVTVGNG
V
GFFLRPYNFFDQ
EPSMDSADSIYFREGQDAGSCEINPLACLPQAATCAPD
LPVFSHGGYPEY
Original
MFIFIFLSLWTLLVMGREEGGVGSEEGVGKQCHPSLPPRCPSRSPSDQPW
THPDQSQLFADLSREELTTVMSFLTQQLGPDLVDAAQARPSDNCVFSVEL
QLPPKAAALAHLDRGSPPPAREALAIVFFGGQPQPNVTELVVGPLPQPSY
MRDVTVERHGGPLPYYRRPVLLREYLDIDQMIFNRELPQAAGVLHHCCSY
KQGGQKLLTMNSAPRGVQSGDRSTWFGIYYNITKGGPYLHPVGLELLVDH
KALDPADWTVQKVFFQGRYYENLAQLEEQFEAGQVNVVVIPDDGTGGFWS
LKSQVPPGPTPPLQFHPQGPRFSVQGNRVASSLWTFSFGLGAFSGPRVFD
VRFQGERLAYEISLQEAGAVYGGNTPAAMLTRYMDSGFGMGYFATPLIRG
VDCPYLATYMDWHFVVESQTPKTLHDAFCVFEQNKGLPLRRHHSDFLSHY
FGGVAQTVLVFRSVSTMLNYDYVWDMVFYPNGAIEVKLHATGYISSAFLF
GAARRYGNQVGEHTLGPVHTHSAHYKVDLDVGGLENWVWAEDMAFVPTAI
PWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHPR
GYRIQTVSFAGGPMPQNSPMERAFSWGRYQLAITQRKETEPSSSSVFNQN
DPWTPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGV
GFFLRPYNFFDQEPSMDSADSIYFREGQDAGSCEINPLACLPQAATCAPD
LPVFSHGGYPEY
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11