Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P15943 (Created: 1990-04-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

APLP2_RAT

Protein Name

Amyloid-like protein 2

Gene

Aplp2

Organism Scientific

Rattus norvegicus

Organism Common

Rat

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Rattus

Protein Length [aa]

765

Protein Mass [Da]

86883

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   29
chain   Amyloid-like protein 2      30   765
disulfide bond      by similarity   312   362
disulfide bond      by similarity   321   345
disulfide bond      by similarity   337   358
transmembrane region      potential   696   718
topological domain   Extracellular   potential   30   695
topological domain   Cytoplasmic   potential   719   765
domain   BPTI/Kunitz inhibitor      308   366
modified residue   Phosphotyrosine   by similarity   752   752
modified residue   Phosphotyrosine   by similarity   757   757
glycosylation site   O-linked (Xyl...) (glycosaminoglycan)   potential   628   628
site   Reactive bond   by similarity   322   323
splice variant   (in isoform C, isoform D)      311   365
splice variant   (in isoform B, isoform D)      616   627
compositionally biased region   Poly-Glu      218   229
compositionally biased region   Asp/Glu-rich (highly acidic)      218   282

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MAATGTAAAAATGKLLVLLLLGLTAPAAA

Sequence

MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEP
QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQI
TNVMEANQPVNIDSWCRRDKKQCRSHIVIPFKCLVGEFVSDVLLVPENCQ
FFHQERMEVCEKHQRWHTVVKEACLTEGMTLYSYGMLLPCGVDQFHGTEY
VCCPQTKVVDSDSTMSKEEEEEEEEDEEEDYALDKSEFPTEADLEDFTEA
AADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEPSSDGTIS
DKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRN
NFESEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLE
IRHRSRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASE
KQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVR
AENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY
KVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSEESEEIPP
FHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNK
MDENMVIDETLDVKEMIFNAERVGGLEEEPDSVGPLREDFSLSSSALIGL
LVIAVAIATVIVISLVMLRKRQYGTISHGIVEVHPMLTPEERHLNKMQNH
GYENPTYKYLEQMQI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website