Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9TNN7 (Created: 2003-08-22 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

1C05_HUMAN

Protein Name

HLA class I histocompatibility antigen, Cw-5 alpha chain

Gene

HLA-C

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

366

Protein Mass [Da]

40912

Features

TypeDescriptionStatusStartEnd
signal peptide         1   24
chain   HLA class I histocompatibility antigen, Cw-5 alpha chain      25   366
disulfide bond      by similarity   125   188
disulfide bond      by similarity   227   283
transmembrane region      potential   309   333
topological domain   Extracellular   potential   25   308
topological domain   Cytoplasmic   potential   334   366
domain   Ig-like C1-type      209   297
region of interest   Alpha-1      25   114
region of interest   Alpha-2      115   206
region of interest   Alpha-3      207   298
region of interest   Connecting peptide      299   308
glycosylation site   N-linked (GlcNAc...)   by similarity   110   110
sequence variant   (in allele Cw*0504)      0   0
sequence variant   (in allele Cw*0504)      0   0
sequence variant   (in allele Cw*0502)      0   0
sequence variant   (in allele Cw*0503)      0   0
sequence variant   (in allele Cw*0503)      0   0
sequence variant   (in allele Cw*0503)      0   0

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MRVMAPRTLILLLSGALALTETWA

Sequence

MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPRFIAVG
YVDDTQFVQFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRV
NLRKLRGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYNQFAYDGKDYIAL
NEDLRSWTAADKAAQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGK
KTLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQ
DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWGP
SSQPTIPIVGIVAGLAVLAVLAVLGAVMAVVMCRRKSSGGKGGSCSQAAS
SNSAQGSDESLIACKA

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website