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Signal Peptide Database - Bacteria
Entry Details
ID
76
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P0AD64 (Created: 2005-12-06 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
BLA1_KLEPN
Protein Name
Beta-lactamase SHV-1
Gene
bla
Organism Scientific
Klebsiella pneumoniae
Organism Common
Lineage
Bacteria
Proteobacteria
Gammaproteobacteria
Enterobacteriales
Enterobacteriaceae
Klebsiella
Protein Length [aa]
286
Protein Mass [Da]
31224
Features
Type
Description
Status
Start
End
signal peptide
1
21
chain
Beta-lactamase SHV-1
22
286
disulfide bond
73
119
region of interest
Substrate binding
230
232
strand
37
46
strand
52
57
strand
192
195
strand
211
213
strand
226
233
strand
239
247
strand
253
261
helix
25
36
helix
65
67
helix
68
81
helix
95
97
helix
105
108
helix
115
125
helix
128
137
helix
140
150
helix
164
166
helix
179
191
helix
197
208
helix
214
220
helix
235
237
helix
266
282
active site
Acyl-ester intermediate
66
66
active site
Proton acceptor
164
164
turn
47
49
turn
109
111
SP Length
21
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MRYIRLCIISLLATLPLAVHA
Sequence
MRYIRLCIISLLATLPLAVHA
SPQ
PLEQIKLSESQL
SGRVGMIEMD
LAS
G
R
TLTAWR
ADERFPM
M
S
T
FKVVLCGAVLARVD
AGDEQLERKIHYR
QQD
LVD
YSPV
SEKH
LAD
GMT
VGELCAAAITM
SD
NSAANLLLAT
VG
GPAGLTAFLRQ
IGDNVTRLDRWET
E
LN
EALPGDARDTTT
PASMAATLRKLLT
SQRL
S
ARSQ
RQLLQWMV
DD
RVA
GPLIRSV
LPAGW
FIADKTGA
G
ERG
A
RGIVALLGP
NNK
AE
RIVVIYLRD
TPAS
MAERNQQIAGIGAALIE
HWQR
Original
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASG
RTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVD
YSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQ
IGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQ
RQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNK
AERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11