Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P12643 (Created: 1989-10-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

BMP2_HUMAN

Protein Name

Bone morphogenetic protein 2

Gene

BMP2

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

396

Protein Mass [Da]

44702

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   23
chain   Bone morphogenetic protein 2      283   396
disulfide bond         296   361
disulfide bond         325   393
disulfide bond         329   395
disulfide bond   Interchain      360   360
glycosylation site   N-linked (GlcNAc...)   potential   135   135
glycosylation site   N-linked (GlcNAc...)   potential   163   163
glycosylation site   N-linked (GlcNAc...)   potential   164   164
glycosylation site   N-linked (GlcNAc...)   potential   200   200
sequence variant   (in dbSNP:rs11545591)      0   0
sequence variant   (in dbSNP:rs235768)      0   0
sequence variant   (in dbSNP:rs34183594)      0   0
sequence variant   (in dbSNP:rs2273074)      0   0
sequence variant   (in dbSNP:rs36105541)      0   0
sequence variant   (in dbSNP:rs2273073)      0   0
strand         295   299
strand         302   304
strand         314   316
strand         318   321
strand         324   326
strand         360   374
strand         380   396
helix         305   308
helix         335   337
helix         341   352
propeptide         24   282
turn         311   313

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MVAGTRCLLALLLPQVLLGGAAG

Sequence

MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVL
SEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLE
RAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAEL
QVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQN
ASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSL
HQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVN
SVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website