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Signal Peptide Database - Mammalia
Entry Details
ID
93
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
Q5R9X1 (Created: 2005-11-08 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
CADH2_PONAB
Protein Name
Cadherin-2
Gene
CDH2
Organism Scientific
Pongo abelii
Organism Common
Sumatran orangutan
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Euarchontoglires
Primates
Haplorrhini
Catarrhini
Hominidae
Pongo
Protein Length [aa]
906
Protein Mass [Da]
99838
Features
Type
Description
Status
Start
End
signal peptide
potential
1
25
chain
Cadherin-2
160
906
transmembrane region
potential
725
745
topological domain
Extracellular
potential
160
724
topological domain
Cytoplasmic
potential
746
906
domain
Cadherin 1
160
267
domain
Cadherin 2
268
382
domain
Cadherin 3
383
497
domain
Cadherin 4
498
603
domain
Cadherin 5
604
710
modified residue
Phosphotyrosine
by similarity
785
785
glycosylation site
N-linked (GlcNAc...)
potential
190
190
glycosylation site
N-linked (GlcNAc...)
potential
273
273
glycosylation site
N-linked (GlcNAc...)
potential
325
325
glycosylation site
N-linked (GlcNAc...)
potential
402
402
glycosylation site
N-linked (GlcNAc...)
potential
572
572
glycosylation site
N-linked (GlcNAc...)
potential
622
622
glycosylation site
N-linked (GlcNAc...)
potential
651
651
glycosylation site
N-linked (GlcNAc...)
potential
692
692
propeptide
by similarity
26
159
compositionally biased region
Ser-rich
863
878
SP Length
25
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MCRIAGALRTLLPLLAALLQASVEA
Sequence
MCRIAGALRTLLPLLAALLQASVEA
SGEIALCKTGFPEDVYSAVLSKDVH
EGQPLLNVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHA
KFLIYAQEEETQEKWQVAVKLSLKPTLTEESVKESAEVEEIVFPRQFSKH
SGHLQRQKR
DWVIPPINLPENSRGPFPQELVRIRSDRDK
N
LSLRYSVTGP
GADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENP
IDIVINVIDMNDNRPEF
LHQVW
N
GTVPEGSKPGTYVMTVTAIDADDPNAL
NGMLRYRILSQAPSTPSPNMFTIN
N
ETGDIITVAAGLDREKVQQYTLIIQ
ATDMEGNPTYGLSNTATAIITVTDVNDNPPEF
TAMTFYGEVPENRVDVIV
A
N
LTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI
DFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYF
APN
PKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN
GQITTIAVLDRESPNVKNNIY
N
ATFLASDNGIPPMSGTGTLQIYLLDIND
NAP
QVLPQEAETCETPDPNSI
N
ITALDYDIDPNAGPFAFDLPLSPVTIKR
N
WTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKS
N
ISILRVKV
CQCDSNGDCT
DVDRIVGAGLGTGA
IIAILLCIIILLILVLMFVVW
MKRRD
KERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD
Y
DLSQLQQPDTVEPDA
IKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAP
PYDSLLVFDYEG
SGSTAGSLSSLNSSSS
GGEQDYDYLNDWGPRFKKLADM
YGGGDD
Original
MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVH
EGQPLLNVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHA
KFLIYAQEEETQEKWQVAVKLSLKPTLTEESVKESAEVEEIVFPRQFSKH
SGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGP
GADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENP
IDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL
NGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQ
ATDMEGNPTYGLSNTATAIITVTDVNDNPPEFTAMTFYGEVPENRVDVIV
ANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI
DFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPN
PKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN
GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDIND
NAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKR
NWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKV
CQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRD
KERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDA
IKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAP
PYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM
YGGGDD
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11