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Signal Peptide Database - Mammalia
Entry Details
ID
94
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
O54800 (Created: 2001-04-27 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
CADH8_RAT
Protein Name
Cadherin-8
Gene
Cdh8
Organism Scientific
Rattus norvegicus
Organism Common
Rat
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Euarchontoglires
Glires
Rodentia
Sciurognathi
Muroidea
Muridae
Murinae
Rattus
Protein Length [aa]
799
Protein Mass [Da]
88333
Features
Type
Description
Status
Start
End
signal peptide
potential
1
29
chain
Cadherin-8
62
799
transmembrane region
potential
622
642
topological domain
Extracellular
potential
62
621
topological domain
Cytoplasmic
potential
643
799
domain
Cadherin 1
62
167
domain
Cadherin 2
168
276
domain
Cadherin 3
277
391
domain
Cadherin 4
392
494
domain
Cadherin 5
495
616
glycosylation site
N-linked (GlcNAc...)
potential
188
188
glycosylation site
N-linked (GlcNAc...)
potential
463
463
glycosylation site
N-linked (GlcNAc...)
potential
473
473
glycosylation site
N-linked (GlcNAc...)
potential
544
544
splice variant
(in isoform 2)
0
0
splice variant
(in isoform 2)
533
799
propeptide
potential
30
61
SP Length
29
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MPERLAETLLDLWTPLIILWITLPSFVYM
Sequence
MPERLAETLLDLWTPLIILWITLPSFVYM
APMNQAHVLTTGSPLELSRQS
EEMRILNRSKR
GWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYIL
SGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPP
SEFIIKVQDINDNAPEF
LNGPYHATVPEMSILGTSVT
N
VTATDADDPVYG
NSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMG
GHSGGLSGTTTLTVTLTDVNDNPPKF
AQSLYHFSVPEDVVLGTAIGRVKA
NDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKS
YTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVF
SSPTYLLEV
HENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITL
ATPLDRELSVWH
N
ISIIATEIR
N
HSQISRVPVAIKVLDVNDNAP
EFASEY
EAFLCENGKPGQVIQTVSAMDKDDPKNGHFFL
YSLLPEMVNNPNFTIKKN
EDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCS
NDGVVQSCNVEPYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNE
PLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDI
KPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYE
GRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET
Original
MPERLAETLLDLWTPLIILWITLPSFVYMAPMNQAHVLTTGSPLELSRQS
EEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYIL
SGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPP
SEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYG
NSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMG
GHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKA
NDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKS
YTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEV
HENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITL
ATPLDRELSVWHNISIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEY
EAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKN
EDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCS
NDGVVQSCNVEPYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNE
PLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDI
KPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYE
GRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11