Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

27025

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P18168 (Created: 1990-11-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

SERR_DROME

Protein Name

Serrate protein

Gene

Ser

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

1404

Protein Mass [Da]

150344

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   79
chain   Serrate protein      80   1404
disulfide bond      by similarity   284   295
disulfide bond      by similarity   288   301
disulfide bond      by similarity   303   312
disulfide bond      by similarity   315   326
disulfide bond      by similarity   321   333
disulfide bond      by similarity   335   344
disulfide bond      by similarity   351   363
disulfide bond      by similarity   357   373
disulfide bond      by similarity   375   384
disulfide bond      by similarity   391   402
disulfide bond      by similarity   396   473
disulfide bond      by similarity   475   484
disulfide bond      by similarity   491   502
disulfide bond      by similarity   496   511
disulfide bond      by similarity   513   522
disulfide bond      by similarity   529   584
disulfide bond      by similarity   578   593
disulfide bond      by similarity   595   604
disulfide bond      by similarity   611   621
disulfide bond      by similarity   615   630
disulfide bond      by similarity   632   641
disulfide bond      by similarity   648   659
disulfide bond      by similarity   653   668
disulfide bond      by similarity   670   679
disulfide bond      by similarity   686   696
disulfide bond      by similarity   691   705
disulfide bond      by similarity   707   716
disulfide bond      by similarity   766   781
disulfide bond      by similarity   783   792
disulfide bond      by similarity   799   810
disulfide bond      by similarity   804   819
disulfide bond      by similarity   821   830
disulfide bond      by similarity   837   848
disulfide bond      by similarity   842   861
disulfide bond      by similarity   863   872
disulfide bond      by similarity   879   890
disulfide bond      by similarity   884   899
disulfide bond      by similarity   901   910
disulfide bond      by similarity   917   928
disulfide bond      by similarity   922   937
disulfide bond      by similarity   939   948
transmembrane region      potential   1220   1245
topological domain   Extracellular   potential   80   1219
topological domain   Cytoplasmic   potential   1246   1404
domain   DSL      235   279
domain   EGF-like 1      280   313
domain   EGF-like 2      311   345
domain   EGF-like 3      347   385
domain   EGF-like 4      387   485
domain   EGF-like 5; calcium-binding   potential   487   523
domain   EGF-like 6; calcium-binding   potential   525   605
domain   EGF-like 7; calcium-binding   potential   607   642
domain   EGF-like 8; calcium-binding   potential   644   680
domain   EGF-like 9      682   717
domain   EGF-like 10      719   793
domain   EGF-like 11; calcium-binding   potential   795   831
domain   EGF-like 12      833   873
domain   EGF-like 13      875   911
domain   EGF-like 14; calcium-binding   potential   913   949
modified residue   Phosphoserine      1292   1292
glycosylation site   N-linked (GlcNAc...)   potential   148   148
glycosylation site   N-linked (GlcNAc...)   potential   192   192
glycosylation site   N-linked (GlcNAc...)   potential   243   243
glycosylation site   N-linked (GlcNAc...)   potential   327   327
glycosylation site   N-linked (GlcNAc...)   potential   408   408
glycosylation site   N-linked (GlcNAc...)   potential   448   448
glycosylation site   N-linked (GlcNAc...)   potential   554   554
glycosylation site   N-linked (GlcNAc...)   potential   735   735
glycosylation site   N-linked (GlcNAc...)   potential   961   961
glycosylation site   N-linked (GlcNAc...)   potential   973   973
glycosylation site   N-linked (GlcNAc...)   potential   1000   1000
glycosylation site   N-linked (GlcNAc...)   potential   1026   1026
glycosylation site   N-linked (GlcNAc...)   potential   1146   1146
compositionally biased region   Ser-rich      403   472
compositionally biased region   Thr-rich      733   765

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLP
STIRDCRSLKSACNLIALILILLVHKISA

Sequence

MFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLP
STIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNG
YCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNAT
TKILGGSSFVLSDPGVGAIVLPFTFRWTKSFTLILQALDMYNTSYPDAER
LIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFC
RPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGE
CECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNF
CGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGG
TCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGS
SSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGG
TCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAI
IGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWG
GVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECAT
SPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEGHCLNTP
EGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTTTTT
TATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECS
PNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMP
GAPDKALQPHCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCV
CAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEI
LLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCEN
GTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPC
NVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVG
KGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVE
LTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTS
IVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRT
SSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGME
LSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQ
ILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGSDVLAT
TVMV

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website