Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

29570

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P18537 (Created: 1990-11-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

FRIZ_DROME

Protein Name

Frizzled

Gene

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

581

Protein Mass [Da]

64847

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   18
chain   Frizzled      19   581
disulfide bond      by similarity   53   114
disulfide bond      by similarity   61   107
disulfide bond      by similarity   98   134
disulfide bond      by similarity   124   163
disulfide bond      by similarity   128   151
transmembrane region   1   probable   248   270
transmembrane region   2   probable   281   303
transmembrane region   3   probable   344   364
transmembrane region   4   probable   381   401
transmembrane region   5   probable   422   439
transmembrane region   6   probable   472   492
transmembrane region   7   probable   530   553
topological domain   Extracellular   probable   19   247
topological domain   Cytoplasmic   probable   271   280
topological domain   Extracellular   probable   304   343
topological domain   Cytoplasmic   probable   365   380
topological domain   Extracellular   probable   402   421
topological domain   Cytoplasmic   probable   440   471
topological domain   Extracellular   probable   493   529
topological domain   Cytoplasmic   probable   554   581
domain   FZ      48   166
glycosylation site   N-linked (GlcNAc...)   potential   67   67
glycosylation site   N-linked (GlcNAc...)   potential   167   167
splice variant   (in isoform II)      0   0
splice variant   (in isoform II)      416   581
short sequence motif   Lys-Thr-X-X-X-Trp motif      556   561
short sequence motif   PDZ-binding      579   581

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MWRQILFILPTLIQGVQR

Sequence

MWRQILFILPTLIQGVQRYDQSPLDASPYYRSGGGLMASSGTELDGLPHH
NRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSD
DLQLFLCSLYVPVCTILERPIPPCRSLCESARVCEKLMKTYNFNWPENLE
CSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRN
IGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCHAMFFPERERTVLRYWV
GSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGL
GAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMA
AFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLAL
AKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFR
IRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEW
MIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSV
WLYSSKTMVSWRNFVERLQGKEPRTRAQAYV

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website