Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

29727

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P16621 (Created: 1990-08-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

LAR_DROME

Protein Name

Tyrosine-protein phosphatase Lar

Gene

Lar

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

2029

Protein Mass [Da]

229056

Features

TypeDescriptionStatusStartEnd
signal peptide         1   32
chain   Tyrosine-protein phosphatase Lar      33   2029
disulfide bond      potential   57   111
disulfide bond      potential   161   209
disulfide bond      potential   256   301
transmembrane region      potential   1378   1402
topological domain   Extracellular   potential   33   1377
topological domain   Cytoplasmic   potential   1403   2029
domain   Ig-like C2-type 1      36   128
domain   Ig-like C2-type 2      140   224
domain   Ig-like C2-type 3      234   316
domain   Fibronectin type-III 1      322   410
domain   Fibronectin type-III 2      416   508
domain   Fibronectin type-III 3      515   603
domain   Fibronectin type-III 4      610   704
domain   Fibronectin type-III 5      709   807
domain   Fibronectin type-III 6      812   904
domain   Fibronectin type-III 7      909   1002
domain   Fibronectin type-III 8      1006   1099
domain   Fibronectin type-III 9      1101   1203
domain   Tyrosine-protein phosphatase 1      1474   1729
domain   Tyrosine-protein phosphatase 2      1761   2020
modified residue   Phosphothreonine      1572   1572
glycosylation site   N-linked (GlcNAc...)   potential   176   176
glycosylation site   N-linked (GlcNAc...)   potential   253   253
glycosylation site   N-linked (GlcNAc...)   potential   298   298
glycosylation site   N-linked (GlcNAc...)   potential   553   553
glycosylation site   N-linked (GlcNAc...)   potential   616   616
glycosylation site   N-linked (GlcNAc...)   potential   666   666
glycosylation site   N-linked (GlcNAc...)   potential   721   721
glycosylation site   N-linked (GlcNAc...)   potential   774   774
glycosylation site   N-linked (GlcNAc...)   potential   915   915
glycosylation site   N-linked (GlcNAc...)   potential   962   962
glycosylation site   N-linked (GlcNAc...)   potential   1183   1183
glycosylation site   N-linked (GlcNAc...)   potential   1304   1304
active site   Phosphocysteine intermediate   by similarity   1670   1670
active site   Phosphocysteine intermediate   by similarity   1961   1961

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MGLQMTAARPIAALSLLVLSLLTWTHPTIVDA

Sequence

MGLQMTAARPIAALSLLVLSLLTWTHPTIVDAAHPPEIIRKPQNQGVRVG
GVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPV
RAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRV
IEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSR
EEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGS
NLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYT
CIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL
QYYVIQYKPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGR
GPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGY
KVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAG
PMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYEL
YWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPP
IPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFF
VEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPI
ILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQE
LRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS
AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLR
WGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQETVK
IFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFH
KKIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIV
ETERDMGRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVED
LDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIK
PEDVPLNLRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFS
QTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAIPSDYSYRPPTKIT
VTTQMAAPQPMVKPDFYGVVNGEEILVILPQASEEYGPISHYYLVVVPED
KSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSGD
DYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREAPP
GERPHRPDPNWPAEPEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLC
VVKRRRQPCKTPDQAAVTRPLMAADLGAGPTPSDPVDMRRLNFQTPGMIS
HPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSK
NRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQ
ETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVT
ITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQ
FLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYG
HVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL
ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYES
SRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLW
EHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYK
LREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQ
FGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQR
PAMVQTEDQYHFCYRAALEYLGSFDNYTN

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website