Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

3340

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9VSL7 (Created: 2005-02-15 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

FOI_DROME

Protein Name

Zinc transporter foi

Gene

foi

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

706

Protein Mass [Da]

77376

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   21
chain   Zinc transporter foi      22   706
transmembrane region   1   potential   262   282
transmembrane region   2   potential   293   313
transmembrane region   3   potential   330   350
transmembrane region   4   potential   605   625
transmembrane region   5   potential   632   652
transmembrane region   6   potential   666   686
topological domain   Extracellular   potential   22   261
topological domain   Cytoplasmic   potential   283   292
topological domain   Extracellular   potential   314   329
topological domain   Cytoplasmic   potential   351   604
topological domain   Extracellular   potential   626   631
topological domain   Cytoplasmic   potential   653   665
topological domain   Extracellular   potential   687   706
modified residue   Phosphoserine      376   376
modified residue   Phosphoserine      377   377
modified residue   Phosphoserine      381   381
glycosylation site   N-linked (GlcNAc...)   potential   74   74
glycosylation site   N-linked (GlcNAc...)   potential   119   119
glycosylation site   N-linked (GlcNAc...)   potential   176   176
glycosylation site   N-linked (GlcNAc...)   potential   182   182
glycosylation site   N-linked (GlcNAc...)   potential   196   196
glycosylation site   N-linked (GlcNAc...)   potential   207   207
mutagenesis site   4-fold reduction in zinc transport activity in yeast assay      0   0
mutagenesis site   Severely reduced zinc transport activity in yeast assay      0   0
mutagenesis site   2-fold reduction in zinc transport activity in yeast assay; when in association with A-588 and A-591      0   0
mutagenesis site   2-fold reduction in zinc transport activity in yeast assay; when in association with A-584 and A-591      0   0
mutagenesis site   2-fold reduction in zinc transport activity in yeast assay; when in association with A-584 and A-588      0   0
mutagenesis site   2-fold reduction zinc transport activity in yeast assay      0   0

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MARHIMAVCVVCLLCAHRLHC

Sequence

MARHIMAVCVVCLLCAHRLHCQDHIESLLGPARVTTHNSQDQLNARVYTN
LSPSSETTDRRQQRSASGDDDTFNYSISPPSRREKRHAGHEHGPTSESRV
PQITQYYLEKLMAQDELMNSSGFDGLLQQLSLHSLASGASEGTCVPGSRL
VHHVQPHDHHHAHHHEEEDHSLQLNNCTLIQNGTTSNVICPSLPNNNTHP
LGKEAKNFTLSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLE
AEKDKDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVAL
AVGTMTGDALLHLLPHSLAGQDERGMIMKGLGCLGGIIFFYVMEHALTMI
SEWRKSVEKKETKKPSRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYD
EITMNNKQSEWMHLPFDVAAGAGGDAPSVAELRNGVGDHDGSNDMAAAAE
SLISPLHTNCVEMNHHNHNHKHNSHQQNHEGQDSNTIVTDLDGNAVYAVN
KAKDKDSRNDHVTVILREHESSHHGHSHRHGHVHSPPETLSAVAWMIIMG
DGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGM
SVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALV
DMMPEISASHKSLGQFLLQILGMLSGVGIMLLIALYEGDLMSAFGTAGAA
SHQHAH

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

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