Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

4428

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P56674 (Created: 1999-07-15 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HH_DROHY

Protein Name

Protein hedgehog

Gene

Organism Scientific

Drosophila hydei

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila

Protein Length [aa]

422

Protein Mass [Da]

47407

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   31
chain   Protein hedgehog      32   422
chain   Protein hedgehog N-product      32   205
chain   Protein hedgehog C-product      206   422
site   Cleavage; by autolysis   by similarity   205   206
site   Involved in cholesterol transfer   by similarity   251   251
site   Involved in auto-cleavage   by similarity   274   274
site   Essential for auto-cleavage   by similarity   277   277
lipid moiety-binding region   N-palmitoyl cysteine   by similarity   32   32
lipid moiety-binding region   Cholesterol glycine ester   by similarity   205   205

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MRHIAHTPRGSCFMALLLLLLLALNFRHAHS

Sequence

MRHIAHTPRGSCFMALLLLLLLALNFRHAHSCGPGRGLGRRRERNLFPLV
LKQTVPNLSEYHNSASGPLEGAIQRDSPKFKNLVLNYNRDIEFRDEEGTG
ADRVMSKRCREKLNMLAYSVMNEWPGVRLRVTESWDEDRQHGQESLHYEG
RAVTIATSDHDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSPSI
SHMHGCFTPESTALLESGAEKALGELAIGDRVLSMDVKGQPVYSEVILFM
DRNLEQVENFVQLHTDGGAVLTVTPAHLISVWQPERQTLNFIFADRVEEL
DYVLVRDATGELQPQRVLRLGSVQSRGVVAPLTREGTIVVNSVAASCYAV
ISSQSLAHWGLAPMRLLSTLQSWMPAKGQLRTAQDKSTPKDATAQQQNGL
HWYANALYKVKDYVLPKSWRHD

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website