Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

5334

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9VW71 (Created: 2002-11-15 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

FAT2_DROME

Protein Name

Putative fat-like cadherin-related tumor suppressor homolog

Gene

fat2

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

4705

Protein Mass [Da]

524576

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   35
chain   Putative fat-like cadherin-related tumor suppressor homolog      36   4705
disulfide bond      potential   3823   3835
disulfide bond      potential   3830   3867
disulfide bond      potential   3869   3878
disulfide bond      potential   3885   3896
disulfide bond      potential   3890   3907
disulfide bond      potential   3909   3918
disulfide bond      by similarity   4087   4121
disulfide bond      potential   4133   4144
disulfide bond      potential   4138   4154
disulfide bond      potential   4156   4165
disulfide bond      potential   4172   4183
disulfide bond      potential   4177   4193
disulfide bond      potential   4195   4204
disulfide bond      by similarity   4210   4221
disulfide bond      by similarity   4215   4230
disulfide bond      by similarity   4232   4240
disulfide bond      potential   4247   4258
disulfide bond      potential   4252   4267
disulfide bond      potential   4269   4278
transmembrane region      potential   4302   4322
topological domain   Extracellular   potential   36   4301
topological domain   Cytoplasmic   potential   4323   4705
domain   Cadherin 1      60   180
domain   Cadherin 2      181   288
domain   Cadherin 3      285   397
domain   Cadherin 4      398   504
domain   Cadherin 5      505   610
domain   Cadherin 6      611   713
domain   Cadherin 7      770   874
domain   Cadherin 8      875   977
domain   Cadherin 9      978   1085
domain   Cadherin 10      1086   1195
domain   Cadherin 11      1191   1296
domain   Cadherin 12      1297   1402
domain   Cadherin 13      1405   1503
domain   Cadherin 14      1504   1609
domain   Cadherin 15      1610   1714
domain   Cadherin 16      1715   1812
domain   Cadherin 17      1813   1929
domain   Cadherin 18      1930   2030
domain   Cadherin 19      2031   2137
domain   Cadherin 20      2138   2238
domain   Cadherin 21      2239   2338
domain   Cadherin 22      2339   2465
domain   Cadherin 23      2466   2567
domain   Cadherin 24      2568   2670
domain   Cadherin 25      2671   2779
domain   Cadherin 26      2780   2876
domain   Cadherin 27      2877   2983
domain   Cadherin 28      2984   3088
domain   Cadherin 29      3084   3185
domain   Cadherin 30      3186   3289
domain   Cadherin 31      3290   3394
domain   Cadherin 32      3395   3499
domain   Cadherin 33      3500   3604
domain   Cadherin 34      3605   3712
domain   EGF-like 1      3819   3879
domain   EGF-like 2      3881   3919
domain   Laminin G-like      3937   4121
domain   EGF-like 3      4129   4166
domain   EGF-like 4      4168   4205
domain   EGF-like 5      4243   4279
glycosylation site   N-linked (GlcNAc...)   potential   65   65
glycosylation site   N-linked (GlcNAc...)   potential   156   156
glycosylation site   N-linked (GlcNAc...)   potential   364   364
glycosylation site   N-linked (GlcNAc...)   potential   779   779
glycosylation site   N-linked (GlcNAc...)   potential   843   843
glycosylation site   N-linked (GlcNAc...)   potential   923   923
glycosylation site   N-linked (GlcNAc...)   potential   1106   1106
glycosylation site   N-linked (GlcNAc...)   potential   1198   1198
glycosylation site   N-linked (GlcNAc...)   potential   1312   1312
glycosylation site   N-linked (GlcNAc...)   potential   1439   1439
glycosylation site   N-linked (GlcNAc...)   potential   1473   1473
glycosylation site   N-linked (GlcNAc...)   potential   1511   1511

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQS

Sequence

MKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLE
NQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYR
IISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHV
HLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSIL
KVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFE
LTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTS
NPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIEL
NQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQE
IYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPD
SGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDN
DPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVP
FEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVV
KDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDG
NEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVH
LMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVF
SDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGY
NGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLG
NPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATD
ADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAK
DGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIE
AVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHN
LIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPK
GTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDA
ETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVT
EASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTT
ERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRV
YKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQR
GHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAP
LIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFY
IGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNP
PQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLA
LFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVH
DHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIIT
GNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPV
HIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIIS
GNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIII
HILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDAD
VGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVS
DMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQ
VSAKDADNDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYA
LHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIG
LVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRL
FVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDD
PKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVE
GHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKED
VEMYSALSVSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYE
KISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPEN
ASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYL
KTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYD
SIIPVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSL
EYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAY
ARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYA
NLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGK
FGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIV
DNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVR
ASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTK
LHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAET
STVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSA
TDADTGPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYN
FKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGT
VLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLM
FYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGT
TLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPK
YKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQL
NTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRE
TISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILE
NATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNA
TLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYR
INVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGT
ISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFS
SSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRL
EQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQY
PPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQ
SSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVT
NDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQS
DYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTL
IDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTF
TDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSG
SALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKI
NKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYR
FDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPG
VNGILNIQSNDIFVGAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPL
YISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTD
VFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLS
GKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQ
PCGNGATCINEPGSFRCICPSYLTGASCGDPLYSNSISTKLKNFSIEHIS
GIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNS
LVDKDNYCKPNVKLSNLEVNQRPISYTAVPNDNLVLSNRNFVNNLDILRS
YGSAGDELENVPFEYQKVNRNKQHVNINSCHSTDADNAYKQEWCEQMHLR
TFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALA
NGQYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAF
FVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSR
LSSFNNIENEDYKSNTGKVYLRHPDSYLPTMHFPSETDGESSMTEGPISR
MEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQ
QQTNN

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website