Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

5787

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P35832 (Created: 1994-06-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

PTP99_DROME

Protein Name

Tyrosine-protein phosphatase 99A

Gene

Ptp99A

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

1301

Protein Mass [Da]

145396

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   28
chain   Tyrosine-protein phosphatase 99A      29   1301
transmembrane region      potential   395   415
topological domain   Extracellular   potential   29   394
topological domain   Cytoplasmic   potential   416   1301
domain   Fibronectin type-III 1      66   165
domain   Fibronectin type-III 2      171   265
domain   Fibronectin type-III 3      271   365
domain   Tyrosine-protein phosphatase 1      476   741
domain   Tyrosine-protein phosphatase 2      764   1016
glycosylation site   N-linked (GlcNAc...)   potential   33   33
glycosylation site   N-linked (GlcNAc...)   potential   176   176
glycosylation site   N-linked (GlcNAc...)   potential   212   212
glycosylation site   N-linked (GlcNAc...)   potential   278   278
glycosylation site   N-linked (GlcNAc...)   potential   322   322
glycosylation site   N-linked (GlcNAc...)   potential   336   336
active site   Phosphocysteine intermediate   by similarity   682   682
splice variant   (in isoform C)      0   0
splice variant   (in isoform D)      0   0
splice variant   (in isoform A, isoform C)      1050   1119
splice variant   (in isoform D)      1059   1301
compositionally biased region   Ser-rich      34   67
compositionally biased region   Gln-rich      1054   1091
compositionally biased region   Poly-Ser      1124   1128
compositionally biased region   Gln-rich      1228   1252

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MPRPQHHALLRAMLKLLLFASIAEHCAT

Sequence

MPRPQHHALLRAMLKLLLFASIAEHCATALPTNSSNSPSSPSPFTVASLP
PTTASSSSSPAVISTSSFDRNLADLVNPEAETSGSGWESLETEFNLATTV
DSSTQKTAKEPVLGTAATSIEQQDQPPDVPATTLAFANAFPVPVAGEMGN
GNGNYNDATPPYAAVDDNYVPSKPQNLTILDVSANSITMSWHPPKNQNGA
IAGYHVFHIHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYRVIVKAF
TTKNEGEPSDQIAQRTDVGGPSAPAIVNLTCHSQESITIRWRRPYEFYNT
IDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTNSYYEVKVAAA
TFSVINPKKIVLGKFSESRIIQLQPNCEKLQPLLRQSHNDYNLAVLVGII
FSCFGIILIIMAFFLWSRKCFHAAYYYLDDPPHHPNAPQVDWEVPVKIGD
EIRAAVPVNEFAKHVASLHADGDIGFSREYEAIQNECISDDLPCEHSQHP
ENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKGHAFIG
TQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVETY
GVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPD
HGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLK
QIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAIASGETNLM
AEQVEELKNCTPYLEQQYKNIIQFQPKDIHIASAMKQVNSIKNRGAIFPI
EGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQM
VWDHNAQTVVLLSSLDDINFAQFWPDEATPIESDHYRVKFLNKTNKSDYV
SRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCNDYRN
GPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVW
TSSEDIRVIYNILSFLPGNLNLLKRTALRTEFEDVTTATPDLYSKICSNG
NVPQHVILQQQQLHMLQLQQQHLETQQQQQQQQQQQQQQQQTALNETVST
PSTDTNPSLLPILSLLPPTVAPLSSSSSTTPPTPSTPTPQPPQTIQLSSH
SPSDLSHQISSTVANAASPVTPATASASAGATPTTPMTPTVPPTIPTIPS
LASQNSLTLTNANFHTVTNNAADLMEHQQQQMLALMQQQTQLQQQYNTHP
QQHHNNVGDLLMNNADNSPTASPTITNNNHITNNNVTSAAATDAQNLDIV
G

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website