Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

6102

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q24238 (Created: 2003-03-28 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

APH4_DROME

Protein Name

Alkaline phosphatase 4

Gene

Aph-4

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

596

Protein Mass [Da]

65262

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   20
chain   Alkaline phosphatase 4      21   570
disulfide bond      by similarity   539   550
transmembrane region      potential   571   591
glycosylation site   N-linked (GlcNAc...)   potential   262   262
glycosylation site   N-linked (GlcNAc...)   potential   297   297
glycosylation site   N-linked (GlcNAc...)   potential   401   401
glycosylation site   N-linked (GlcNAc...)   potential   464   464
glycosylation site   N-linked (GlcNAc...)   potential   470   470
active site   Phosphoserine intermediate   by similarity   144   144
splice variant   (in isoform B)      1   94
propeptide   Removed in mature form      571   596
metal ion-binding site   Magnesium   by similarity   93   93
metal ion-binding site   Zinc 2   by similarity   93   93
metal ion-binding site   Magnesium   by similarity   202   202
metal ion-binding site   Magnesium   by similarity   204   204
metal ion-binding site   Magnesium   by similarity   369   369
metal ion-binding site   Zinc 1   by similarity   374   374
metal ion-binding site   Zinc 1   by similarity   378   378
metal ion-binding site   Zinc 2   by similarity   415   415
metal ion-binding site   Zinc 2   by similarity   416   416
metal ion-binding site   Zinc 1   by similarity   504   504
lipid moiety-binding region   GPI-anchor amidated asparagine   potential   570   570

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MHCLVILGFLLGSLVAFSWA

Sequence

MHCLVILGFLLGSLVAFSWAGVTTQPPPLIRTLSAGGDIGPQFDVGKTKE
PEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTI
SAGRIYKGQYLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATA
IFSGSKTHYGAIGMDATRSKKNGQQGRVQSVMEWAQKEGKRTGVVTTTRI
THATPAATYAHIYDRDWECDTEVPAESVGFHVDIARQLVENAPGNRFNVI
LGGGMSPMGILNASEVKTTIFEGPTETICTRGDNRNLPAEWLAHHANDTV
PPALVHNRKDLLNVNVKKVDHLMGLFRNNHITYSIAREAGEPSLQEMTET
ALGILERGDESNGFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAV
NNTDPDETLILVTADHSHAVTFNGYALRGADILGTANSHEKNDPMFYETI
SYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYRHLATVPRK
DETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKDFDDSC
EDHKDGQKDRPLDKPNPKRNGATVVGASLIPILTAATAAILRGRGL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website