| Type | Description | Status | Start | End |
| signal peptide | | potential | 1 | 52 |
| chain | Processed neurogenic locus Notch protein | | 0 | 2703 |
| chain | Neurogenic locus Notch protein | | 53 | 2703 |
| disulfide bond | | by similarity | 62 | 73 |
| disulfide bond | | by similarity | 67 | 83 |
| disulfide bond | | by similarity | 85 | 94 |
| disulfide bond | | by similarity | 100 | 111 |
| disulfide bond | | by similarity | 105 | 124 |
| disulfide bond | | by similarity | 126 | 135 |
| disulfide bond | | by similarity | 143 | 154 |
| disulfide bond | | by similarity | 148 | 164 |
| disulfide bond | | by similarity | 166 | 175 |
| disulfide bond | | by similarity | 181 | 192 |
| disulfide bond | | by similarity | 186 | 203 |
| disulfide bond | | by similarity | 205 | 214 |
| disulfide bond | | by similarity | 221 | 232 |
| disulfide bond | | by similarity | 226 | 241 |
| disulfide bond | | by similarity | 243 | 252 |
| disulfide bond | | by similarity | 259 | 270 |
| disulfide bond | | by similarity | 264 | 279 |
| disulfide bond | | by similarity | 281 | 290 |
| disulfide bond | | by similarity | 297 | 308 |
| disulfide bond | | by similarity | 302 | 317 |
| disulfide bond | | by similarity | 319 | 328 |
| disulfide bond | | by similarity | 335 | 349 |
| disulfide bond | | by similarity | 343 | 358 |
| disulfide bond | | by similarity | 360 | 369 |
| disulfide bond | | by similarity | 376 | 387 |
| disulfide bond | | by similarity | 381 | 396 |
| disulfide bond | | by similarity | 398 | 407 |
| disulfide bond | | by similarity | 413 | 424 |
| disulfide bond | | by similarity | 418 | 435 |
| disulfide bond | | by similarity | 437 | 446 |
| disulfide bond | | by similarity | 453 | 465 |
| disulfide bond | | by similarity | 459 | 474 |
| disulfide bond | | by similarity | 476 | 485 |
| disulfide bond | | by similarity | 492 | 503 |
| disulfide bond | | by similarity | 497 | 512 |
| disulfide bond | | by similarity | 514 | 523 |
| disulfide bond | | by similarity | 530 | 541 |
| disulfide bond | | by similarity | 535 | 550 |
| disulfide bond | | by similarity | 552 | 561 |
| disulfide bond | | by similarity | 568 | 579 |
| disulfide bond | | by similarity | 573 | 588 |
| disulfide bond | | by similarity | 590 | 599 |
| disulfide bond | | by similarity | 606 | 616 |
| disulfide bond | | by similarity | 611 | 625 |
| disulfide bond | | by similarity | 627 | 636 |
| disulfide bond | | by similarity | 643 | 654 |
| disulfide bond | | by similarity | 648 | 663 |
| disulfide bond | | by similarity | 665 | 674 |
| disulfide bond | | by similarity | 681 | 692 |
| disulfide bond | | by similarity | 686 | 701 |
| disulfide bond | | by similarity | 703 | 712 |
| disulfide bond | | by similarity | 719 | 730 |
| disulfide bond | | by similarity | 724 | 739 |
| disulfide bond | | by similarity | 741 | 750 |
| disulfide bond | | by similarity | 757 | 768 |
| disulfide bond | | by similarity | 762 | 777 |
| disulfide bond | | by similarity | 779 | 788 |
| disulfide bond | | by similarity | 795 | 806 |
| disulfide bond | | by similarity | 800 | 815 |
| disulfide bond | | by similarity | 817 | 826 |
| disulfide bond | | by similarity | 833 | 844 |
| disulfide bond | | by similarity | 838 | 853 |
| disulfide bond | | by similarity | 855 | 864 |
| disulfide bond | | by similarity | 871 | 882 |
| disulfide bond | | by similarity | 876 | 893 |
| disulfide bond | | by similarity | 895 | 904 |
| disulfide bond | | by similarity | 911 | 923 |
| disulfide bond | | by similarity | 917 | 932 |
| disulfide bond | | by similarity | 934 | 943 |
| disulfide bond | | by similarity | 950 | 961 |
| disulfide bond | | by similarity | 955 | 970 |
| disulfide bond | | by similarity | 972 | 981 |
| disulfide bond | | by similarity | 988 | 999 |
| disulfide bond | | by similarity | 993 | 1008 |
| disulfide bond | | by similarity | 1010 | 1019 |
| disulfide bond | | by similarity | 1026 | 1037 |
| disulfide bond | | by similarity | 1031 | 1046 |
| disulfide bond | | by similarity | 1048 | 1057 |
| disulfide bond | | by similarity | 1064 | 1075 |
| disulfide bond | | by similarity | 1069 | 1084 |
| disulfide bond | | by similarity | 1086 | 1095 |
| disulfide bond | | by similarity | 1102 | 1113 |
| disulfide bond | | by similarity | 1107 | 1122 |
| disulfide bond | | by similarity | 1124 | 1133 |
| disulfide bond | | by similarity | 1140 | 1160 |
| disulfide bond | | by similarity | 1155 | 1169 |
| disulfide bond | | by similarity | 1171 | 1180 |
| disulfide bond | | by similarity | 1187 | 1198 |
| disulfide bond | | by similarity | 1192 | 1207 |
| disulfide bond | | by similarity | 1209 | 1218 |
| disulfide bond | | by similarity | 1225 | 1236 |
| disulfide bond | | by similarity | 1230 | 1245 |
| disulfide bond | | by similarity | 1247 | 1256 |
| disulfide bond | | by similarity | 1263 | 1274 |
| disulfide bond | | by similarity | 1268 | 1283 |
| disulfide bond | | by similarity | 1285 | 1294 |
| disulfide bond | | by similarity | 1301 | 1314 |
| disulfide bond | | by similarity | 1306 | 1323 |
| disulfide bond | | by similarity | 1325 | 1334 |
| disulfide bond | | by similarity | 1341 | 1352 |
| disulfide bond | | by similarity | 1346 | 1361 |
| disulfide bond | | by similarity | 1363 | 1372 |
| disulfide bond | | by similarity | 1379 | 1389 |
| disulfide bond | | by similarity | 1384 | 1400 |
| disulfide bond | | by similarity | 1402 | 1411 |
| disulfide bond | | by similarity | 1419 | 1430 |
| disulfide bond | | by similarity | 1424 | 1439 |
| disulfide bond | | by similarity | 1441 | 1450 |
| disulfide bond | | by similarity | 1482 | 1505 |
| disulfide bond | | by similarity | 1487 | 1500 |
| disulfide bond | | by similarity | 1496 | 1512 |
| disulfide bond | | by similarity | 1522 | 1545 |
| disulfide bond | | by similarity | 1527 | 1540 |
| disulfide bond | | by similarity | 1536 | 1552 |
| disulfide bond | | by similarity | 1559 | 1585 |
| disulfide bond | | by similarity | 1567 | 1580 |
| disulfide bond | | by similarity | 1576 | 1592 |
| transmembrane region | | potential | 1746 | 1766 |
| topological domain | Extracellular | potential | 53 | 1745 |
| topological domain | Cytoplasmic | potential | 1767 | 2703 |
| domain | EGF-like 1 | | 58 | 95 |
| domain | EGF-like 2 | | 96 | 136 |
| domain | EGF-like 3 | | 139 | 176 |
| domain | EGF-like 4 | | 177 | 215 |
| domain | EGF-like 5; calcium-binding | potential | 217 | 253 |
| domain | EGF-like 6 | | 255 | 291 |
| domain | EGF-like 7; calcium-binding | potential | 293 | 329 |
| domain | EGF-like 8; calcium-binding | potential | 331 | 370 |
| domain | EGF-like 9; calcium-binding | potential | 372 | 408 |
| domain | EGF-like 10 | | 409 | 447 |
| domain | EGF-like 11; calcium-binding | potential | 449 | 486 |
| domain | EGF-like 12; calcium-binding | potential | 488 | 524 |
| domain | EGF-like 13; calcium-binding | potential | 526 | 562 |
| domain | EGF-like 14; calcium-binding | potential | 564 | 600 |
| domain | EGF-like 15; calcium-binding | potential | 602 | 637 |
| domain | EGF-like 16; calcium-binding | potential | 639 | 675 |
| domain | EGF-like 17; calcium-binding | potential | 677 | 713 |
| domain | EGF-like 18; calcium-binding | potential | 715 | 751 |
| domain | EGF-like 19; calcium-binding | potential | 753 | 789 |
| domain | EGF-like 20; calcium-binding | potential | 791 | 827 |
| domain | EGF-like 21; calcium-binding | potential | 829 | 865 |
| domain | EGF-like 22 | | 867 | 905 |
| domain | EGF-like 23; calcium-binding | potential | 907 | 944 |
| domain | EGF-like 24; calcium-binding | potential | 946 | 982 |
| domain | EGF-like 25 | | 984 | 1020 |
| domain | EGF-like 26; calcium-binding | potential | 1022 | 1058 |
| domain | EGF-like 27 | | 1060 | 1096 |
| domain | EGF-like 28 | | 1098 | 1134 |
| domain | EGF-like 29 | | 1136 | 1181 |
| domain | EGF-like 30; calcium-binding | potential | 1183 | 1219 |
| domain | EGF-like 31; calcium-binding | potential | 1221 | 1257 |
| domain | EGF-like 32; calcium-binding | potential | 1259 | 1295 |
| domain | EGF-like 33 | | 1297 | 1335 |
| domain | EGF-like 34 | | 1337 | 1373 |
| domain | EGF-like 35 | | 1375 | 1412 |
| domain | EGF-like 36 | | 1415 | 1451 |
| region of interest | Interaction with Nedd4 | | 2325 | 2328 |
| modified residue | Phosphoserine | | 2447 | 2447 |
| glycosylation site | N-linked (GlcNAc...) | potential | 322 | 322 |
| glycosylation site | N-linked (GlcNAc...) | potential | 371 | 371 |
| glycosylation site | N-linked (GlcNAc...) | potential | 430 | 430 |
| glycosylation site | N-linked (GlcNAc...) | potential | 475 | 475 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1045 | 1045 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1157 | 1157 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1242 | 1242 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1271 | 1271 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1521 | 1521 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1594 | 1594 |
| glycosylation site | N-linked (GlcNAc...) | potential | 1627 | 1627 |
| sequence variant | | | 0 | 0 |
| sequence variant | | | 0 | 0 |
| sequence variant | | | 0 | 0 |
| sequence variant | | | 0 | 0 |
| sequence variant | | | 0 | 0 |
| sequence variant | | | 0 | 0 |
| helix | | | 1930 | 1950 |
| helix | | | 1954 | 1960 |
| helix | | | 1964 | 1972 |
| helix | | | 1987 | 1993 |
| helix | | | 1997 | 2004 |
| helix | | | 2021 | 2027 |
| helix | | | 2033 | 2039 |
| helix | | | 2054 | 2060 |
| helix | | | 2064 | 2072 |
| helix | | | 2087 | 2093 |
| helix | | | 2097 | 2105 |
| helix | | | 2120 | 2126 |
| helix | | | 2130 | 2136 |
| repeat | LNR 1 | | 1482 | 1521 |
| repeat | LNR 2 | | 1522 | 1557 |
| repeat | LNR 3 | | 1559 | 1599 |
| repeat | ANK 1 | | 1901 | 1945 |
| repeat | ANK 2 | | 1950 | 1979 |
| repeat | ANK 3 | | 1983 | 2013 |
| repeat | ANK 4 | | 2017 | 2046 |
| repeat | ANK 5 | | 2050 | 2079 |
| repeat | ANK 6 | | 2083 | 2112 |
| repeat | ANK 7 | | 2116 | 2139 |
| compositionally biased region | Poly-Gly | | 2486 | 2498 |
| compositionally biased region | Poly-Gln (OPA repeat) | | 2538 | 2568 |
| compositionally biased region | Poly-Ser | | 2664 | 2667 |
| mutagenesis site | In su42c; deltex-like mutation that induces outstreched wings and variability-fused ocelli | | 0 | 0 |
| mutagenesis site | Abolishes interaction with Nedd4 and reduces ubiquitination | | 0 | 0 |
| mutagenesis site | In mcd5; induces loss of microchaetae sensory precursors | | 0 | 0 |
