Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

9798

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P91682 (Created: 2000-05-30 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

SMO_DROME

Protein Name

Protein smoothened

Gene

smo

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

1036

Protein Mass [Da]

116552

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   31
chain   Protein smoothened      32   1036
disulfide bond      by similarity   90   155
disulfide bond      by similarity   100   148
disulfide bond      by similarity   139   179
disulfide bond      by similarity   172   194
transmembrane region   1   potential   259   279
transmembrane region   2   potential   288   308
transmembrane region   3   potential   340   360
transmembrane region   4   potential   382   402
transmembrane region   5   potential   422   442
transmembrane region   6   potential   470   490
transmembrane region   7   potential   533   553
topological domain   Extracellular   potential   32   258
topological domain   Cytoplasmic   potential   280   287
topological domain   Extracellular   potential   309   339
topological domain   Cytoplasmic   potential   361   381
topological domain   Extracellular   potential   403   421
topological domain   Cytoplasmic   potential   443   469
topological domain   Extracellular   potential   491   532
topological domain   Cytoplasmic   potential   554   1036
domain   FZ      85   206
modified residue   Phosphoserine      658   658
modified residue   Phosphoserine      659   659
modified residue   Phosphoserine      667   667
modified residue   Phosphoserine      670   670
modified residue   Phosphoserine      673   673
modified residue   Phosphoserine      687   687
modified residue   Phosphoserine      690   690
modified residue   Phosphoserine      693   693
glycosylation site   N-linked (GlcNAc...)   potential   55   55
glycosylation site   N-linked (GlcNAc...)   potential   95   95
glycosylation site   N-linked (GlcNAc...)   potential   184   184
glycosylation site   N-linked (GlcNAc...)   potential   195   195
glycosylation site   N-linked (GlcNAc...)   potential   213   213
glycosylation site   N-linked (GlcNAc...)   potential   336   336
glycosylation site   N-linked (GlcNAc...)   potential   419   419
compositionally biased region   Poly-Ser      816   819

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MQYLNFPRMPNIMMFLEVAILCLWVVADASA

Sequence

MQYLNFPRMPNIMMFLEVAILCLWVVADASASSAKFGSTTPASAQQSDVE
LEPINGTLNYRLYAKKGRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTC
FGSKLPYELSSLDLTDFHTEKELNDKLNDYYALKHVPKCWAAIQPFLCAV
FKPKCEKINGEDMVYLPSYEMCRITMEPCRILYNTTFFPKFLRCNETLFP
TKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDD
EHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFL
IACVGWLLQFTSGSREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFL
TAGMVWFVFLTYAWHWRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMA
FSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGYFITRGMVMLF
GLKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFRHA
DEWAQSFRQFIICKISSVFEEKSSCRIENRPSVGVLQLHLLCLFSSGIVM
STWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDK
GRLSITLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMAL
TGAATGNSSSHGPRKNSLDSEISVSVRHVSVESRRNSVDSQVSVKIAEMK
TKVASRSRGKHGGSSSNRRTQRRRDYIAAATGKSSRRRESSTSVESQVIA
LKKTTYPNASHKVGVFAHHSSKKQHNYTSSMKRRTANAGLDPSILNEFLQ
KNGDFIFPFLQNQDMSSSSEEDNSRASQKIQDLNVVVKQQEISEDDHDGI
KIEELPNSKQVALENFLKNIKKSNESNSNRHSRNSARSQSKKSQKRHLKN
PAADLDFRKDCVKYRSNDSLSCSSEELDVALDVGSLLNSSFSGISMGKPH
SRNSKTSCDVGIQANPFELVPSYGEDELQQAMRLLNAASRQRTEAANEDF
GGTELQGLLGHSHRHQREPTFMSESDKLKMLLLPSK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website