Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

115

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P08185 (Created: 1988-08-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

CBG_HUMAN

Protein Name

Corticosteroid-binding globulin

Gene

SERPINA6

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

405

Protein Mass [Da]

45141

Features

TypeDescriptionStatusStartEnd
signal peptide         1   22
chain   Corticosteroid-binding globulin      23   405
glycosylation site   N-linked (GlcNAc...)      31   31
glycosylation site   N-linked (GlcNAc...)      96   96
glycosylation site   N-linked (GlcNAc...)   potential   176   176
glycosylation site   N-linked (GlcNAc...)      260   260
glycosylation site   N-linked (GlcNAc...)      330   330
glycosylation site   N-linked (GlcNAc...)      369   369
sequence variant   (in CBG deficiency; Leuven; decreased cortisol-binding affinity; dbSNP:rs28929488)      0   0
sequence variant   (in CBG deficiency; Lyon; decreased cortisol-binding affinity)      0   0
sequence variant   (in dbSNP:rs2228541)      0   0
strand         59   61
strand         63   65
strand         124   134
strand         154   158
strand         194   209
strand         217   224
strand         227   244
strand         246   268
strand         293   302
strand         305   311
strand         340   353
strand         355   370
strand         375   378
strand         383   389
strand         395   402
helix         39   57
helix         67   78
helix         83   92
helix         102   117
helix         141   151
helix         163   177
helix         213   215
helix         273   278
helix         282   291
helix         313   318
helix         323   325
site   Conserved cysteine within steroid binding domain      250   250
binding site   Corticosteroid   by similarity   254   254
binding site   Corticosteroid   by similarity   286   286
binding site   Corticosteroid   by similarity   393   393
turn         97   99
turn         178   180
turn         332   334
turn         390   392

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MPLLLYTCLLWLPTSGLWTVQA

Sequence

MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSL
YKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTER
SETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHY
YESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNY
IFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPC
QLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLY
IPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAV
LQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLAR
VMNPV

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website