Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

118

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P16870 (Created: 1990-08-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

CBPE_HUMAN

Protein Name

Carboxypeptidase E

Gene

CPE

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

476

Protein Mass [Da]

53151

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   25
chain   Carboxypeptidase E      43   476
glycosylation site   N-linked (GlcNAc...)   potential   139   139
glycosylation site   N-linked (GlcNAc...)   potential   390   390
sequence variant   (in dbSNP:rs34516004)      0   0
sequence variant   (in a colorectal cancer sample; somatic mutation)      0   0
active site   Nucleophile   by similarity   342   342
propeptide   Activation peptide      26   42
metal ion-binding site   Zinc   by similarity   114   114
metal ion-binding site   Zinc   by similarity   117   117
metal ion-binding site   Zinc   by similarity   248   248

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MAGRGGSALLALCGALAACGWLLGA

Sequence

MAGRGGSALLALCGALAACGWLLGAEAQEPGAPAAGMRRRRRLQQEDGIS
FEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVH
EPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTR
IHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYV
NEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGG
DLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPC
RKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPP
EETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDH
DVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGVDFELE
SFSERKEEEKEELMEWWKMMSETLNF

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website