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Signal Peptide Database - Mammalia
Entry Details
ID
148
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P00794 (Created: 1986-07-21 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name
CHYM_BOVIN
Protein Name
Chymosin
Gene
CYM
Organism Scientific
Bos taurus
Organism Common
Bovine
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Laurasiatheria
Cetartiodactyla
Ruminantia
Pecora
Bovidae
Bovinae
Bos
Protein Length [aa]
381
Protein Mass [Da]
42180
Features
Type
Description
Status
Start
End
signal peptide
1
16
chain
Chymosin
59
381
disulfide bond
105
110
disulfide bond
265
269
disulfide bond
308
341
sequence variant
(in chymosin A)
0
0
strand
62
65
strand
67
69
strand
73
80
strand
85
92
strand
98
100
strand
125
135
strand
138
151
strand
154
166
strand
176
182
strand
206
214
strand
223
227
strand
234
242
strand
249
264
strand
269
273
strand
278
283
strand
304
306
strand
317
321
strand
324
328
strand
334
337
strand
340
351
strand
354
356
strand
364
369
strand
374
380
helix
108
111
helix
118
120
helix
170
174
helix
186
188
helix
196
202
helix
231
233
helix
284
294
helix
310
313
helix
330
333
helix
358
361
active site
92
92
active site
274
274
propeptide
Activation peptide
17
58
mutagenesis site
Propeptide is not cleaved
0
0
mutagenesis site
Propeptide is not cleaved
0
0
turn
70
72
turn
81
84
turn
246
248
turn
370
373
SP Length
16
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MRCLVVLLAVFALSQG
Sequence
MRCLVVLLAVFALSQG
AEITRIPLYKGKSLRKALKEHGLLEDFLQKQQYG
ISSKYSGF
GEV
ASVP
L
TNY
LDS
QYFGKIYL
GTPP
QEFTVLF
D
TGSSD
FWV
PSIY
CKS
NACK
NHQRFD
PRK
SSTF
QNLGKPLSIHY
GT
GSMQGILGYDTVT
V
SN
IVDIQQTVGLSTQ
EPG
DVFTY
A
EFDGILG
MAY
PSL
ASEYSIP
VFDNM
MN
RHL
VAQDLFSVY
MDRNGQES
MLTLG
AID
PSY
YTGSLHWVP
VTV
QQY
WQ
FTVDSVTISGVVVA
CEGG
CQAIL
D
TGT
SKLVGP
SSDILNIQQAI
GATQNQ
YGE
FDI
D
CD
NLSY
MPT
VVFEI
NG
KMYPL
T
PSAY
TSQD
QG
FCTSGFQSENH
S
QK
WIL
G
DVFI
RE
YYSVFD
RANN
LVGLAKA
I
Original
MRCLVVLLAVFALSQGAEITRIPLYKGKSLRKALKEHGLLEDFLQKQQYG
ISSKYSGFGEVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWV
PSIYCKSNACKNHQRFDPRKSSTFQNLGKPLSIHYGTGSMQGILGYDTVT
VSNIVDIQQTVGLSTQEPGDVFTYAEFDGILGMAYPSLASEYSIPVFDNM
MNRHLVAQDLFSVYMDRNGQESMLTLGAIDPSYYTGSLHWVPVTVQQYWQ
FTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILNIQQAIGATQNQ
YGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYTSQDQGFCTSGFQSENH
SQKWILGDVFIREYYSVFDRANNLVGLAKAI
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
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