Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

182

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q00495 (Created: 1993-04-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

CSF1R_RAT

Protein Name

Macrophage colony-stimulating factor 1 receptor

Gene

Csf1r

Organism Scientific

Rattus norvegicus

Organism Common

Rat

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Rattus

Protein Length [aa]

978

Protein Mass [Da]

109264

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   19
chain   Macrophage colony-stimulating factor 1 receptor      20   978
disulfide bond      potential   42   84
disulfide bond      potential   127   177
disulfide bond      potential   224   278
disulfide bond      potential   417   483
transmembrane region      potential   512   536
topological domain   Extracellular   potential   20   511
topological domain   Cytoplasmic   potential   537   978
domain   Ig-like C2-type 1      24   104
domain   Ig-like C2-type 2      107   197
domain   Ig-like C2-type 3      204   298
domain   Ig-like C2-type 4      299   397
domain   Ig-like C2-type 5      398   503
domain   Protein kinase      580   914
modified residue   Phosphotyrosine   by similarity   554   554
modified residue   Phosphothreonine   by similarity   560   560
modified residue   Phosphothreonine   by similarity   565   565
modified residue   Phosphotyrosine; by autocatalysis   by similarity   697   697
modified residue   Phosphotyrosine; by autocatalysis   by similarity   706   706
modified residue   Phosphotyrosine; by autocatalysis   by similarity   807   807
glycosylation site   N-linked (GlcNAc...)   potential   45   45
glycosylation site   N-linked (GlcNAc...)   potential   73   73
glycosylation site   N-linked (GlcNAc...)   potential   302   302
glycosylation site   N-linked (GlcNAc...)   potential   335   335
glycosylation site   N-linked (GlcNAc...)   potential   389   389
glycosylation site   N-linked (GlcNAc...)   potential   410   410
glycosylation site   N-linked (GlcNAc...)   potential   449   449
glycosylation site   N-linked (GlcNAc...)   potential   478   478
glycosylation site   N-linked (GlcNAc...)   potential   491   491
active site   Proton acceptor   by similarity   776   776
binding site   ATP   by similarity   614   614
nucleotide phosphate-binding region   ATP   by similarity   586   594

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MELGPPLVLLLATVWHGQG

Sequence

MELGPPLVLLLATVWHGQGAPVIEPSGPELVVEPGETVTLRCVSNGSVEW
DGPISPYWTLDPESPGSTLTTRNATFKNTGTYRCTELEDPMAGSTTIHLY
VKDPAHSWNLLAQEVTVVEGQEAVLPCLITDPALKDSVSLMREGGRQVLR
KTVYFFSAWRGFIIRKAKVLDSNTYVCKTMVNGRESTSTGIWLKVNRVHP
EPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRGDTKLEIPLNS
DFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAY
LNLTSEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQRKLE
FITQRAIYRYTFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPP
EVSVTWMPVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQALQVWND
THPEVLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRAVS
LGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKI
IERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAF
GLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGA
CTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNI
HLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSSDSFFKQDLDKEPSRPLEL
WDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARD
IMNDSNYVVKGNARLPVKWMAPESILYCVYTVQSDVWSYGILLWEIFSLG
LNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPT
FQQICFLLQEQARLERRDQDYANLPSSGGSSGSDSGGGSSGGSSSEPEEE
SSSEHLACCEPGDIAQPLLQPNNYQFAC

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website