Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

262

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q69384 (Created: 2004-05-24 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

ENK2_HUMAN

Protein Name

HERV-K_7p22.1 provirus ancestral Env polyprotein

Gene

ERVK6

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

699

Protein Mass [Da]

79218

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   89
chain   HERV-K_7p22.1 provirus ancestral Env polyprotein      90   699
chain   Surface protein   by similarity   90   465
chain   Transmembrane protein   by similarity   466   699
transmembrane region      potential   633   653
topological domain   Extracellular   potential   90   632
topological domain   Cytoplasmic   potential   654   699
region of interest   Fusion peptide   potential   466   486
modified residue   Phosphothreonine      343   343
modified residue   Phosphoserine      346   346
glycosylation site   N-linked (GlcNAc...)   potential   100   100
glycosylation site   N-linked (GlcNAc...)   potential   128   128
glycosylation site   N-linked (GlcNAc...)   potential   153   153
glycosylation site   N-linked (GlcNAc...)   potential   274   274
glycosylation site   N-linked (GlcNAc...)   potential   355   355
glycosylation site   N-linked (GlcNAc...)   potential   372   372
glycosylation site   N-linked (GlcNAc...)   potential   461   461
glycosylation site   N-linked (GlcNAc...)   potential   507   507
glycosylation site   N-linked (GlcNAc...)   potential   554   554
glycosylation site   N-linked (GlcNAc...)   potential   566   566
glycosylation site   N-linked (GlcNAc...)   potential   585   585
site   Cleavage   by similarity   465   466
compositionally biased region   Poly-Arg      13   20
compositionally biased region   Poly-Ala      94   99

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MNPSEMQRKAPPRRRRHRNRAPLTHKMNKMVTSEEQMKLPSTKKAEPPTW
AQLKKLTQLATKYLENTKVTQTPESMLLAALMIVSMVVS

Sequence

MNPSEMQRKAPPRRRRHRNRAPLTHKMNKMVTSEEQMKLPSTKKAEPPTW
AQLKKLTQLATKYLENTKVTQTPESMLLAALMIVSMVVSLPMPAGAAAAN
YTYWAYVPFPPLIRAVTWMDNPTEVYVNDSVWVPGPIDDRCPAKPEEEGM
MINISIGYHYPPICLGRAPGCLMPAVQNWLVEVPTVSPICRFTYHMVSGM
SLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANS
AVILQNNEFGTIIDWAPRGQFYHNCSGQTQSCPSAQVSPAVDSDLTESLD
KHKHKKLQSFYPWEWGEKGISTPRPKIVSPVSGPEHPELWRLTVASHHIR
IWSGNQTLETRDRKPFYTIDLNSSLTVPLQSCVKPPYMLVVGNIVIKPDS
QTITCENCRLLTCIDSTFNWQHRILLVRAREGVWIPVSMDRPWEASPSVH
ILTEVLKGVLNRSKRFIFTLIAVIMGLIAVTATAAVAGVALHSSVQSVNF
VNDWQKNSTRLWNSQSSIDQKLANQINDLRQTVIWMGDRLMSLEHRFQLQ
CDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDNLTLDISKLKEQIFEA
SKAHLNLVPGTEAIAGVADGLANLNPVTWVKTIGSTTIINLILILVCLFC
LLLVCRCTQQLRRDSDHRERAMMTMAVLSKRKGGNVGKSKRDQIVTVSV

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website