Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

273

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P54759 (Created: 1996-10-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

EPHA7_RAT

Protein Name

Ephrin type-A receptor 7

Gene

Epha7

Organism Scientific

Rattus norvegicus

Organism Common

Rat

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Rattus

Protein Length [aa]

998

Protein Mass [Da]

111953

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   24
chain   Ephrin type-A receptor 7      25   998
transmembrane region      potential   557   577
topological domain   Extracellular   potential   25   556
topological domain   Cytoplasmic   potential   578   998
domain   Fibronectin type-III 1      331   433
domain   Fibronectin type-III 2      443   535
domain   Protein kinase      633   894
domain   SAM      923   987
modified residue   Phosphotyrosine; by autocatalysis   potential   608   608
modified residue   Phosphotyrosine; by autocatalysis   potential   614   614
modified residue   Phosphotyrosine; by autocatalysis   potential   791   791
modified residue   Phosphotyrosine; by autocatalysis   potential   940   940
glycosylation site   N-linked (GlcNAc...)   potential   343   343
glycosylation site   N-linked (GlcNAc...)   potential   410   410
active site   Proton acceptor   by similarity   758   758
splice variant   (in isoform Short)      0   0
binding site   ATP   by similarity   665   665
compositionally biased region   Cys-rich      192   328
nucleotide phosphate-binding region   ATP   by similarity   639   647
short sequence motif   PDZ-binding   potential   996   998

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MVVQTRYPSWIILCYIWLLGFAHT

Sequence

MVVQTRYPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISS
PPSGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFV
ELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIA
ADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKV
YYKKCWSIIENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHC
SAEGEWLVPIGKCICKAGYQQKGDTCEPCGRRFYKSSSQDLQCSRCPTHS
FSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLE
WSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYV
TVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM
KERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSA
SINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEATAVSS
EQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSG
RLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGV
VTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLA
DMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPV
RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE
EGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPSSL
KTPLGTCSRPISPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYN
SLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website