Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

279

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q64176 (Created: 1997-11-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

EST22_MOUSE

Protein Name

Liver carboxylesterase 22

Gene

Es22

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

562

Protein Mass [Da]

61582

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   19
chain   Liver carboxylesterase 22      20   562
disulfide bond      by similarity   88   117
disulfide bond      by similarity   274   285
glycosylation site   N-linked (GlcNAc...)   potential   80   80
glycosylation site   N-linked (GlcNAc...)   potential   276   276
glycosylation site   N-linked (GlcNAc...)   potential   490   490
active site   Acyl-ester intermediate   by similarity   222   222
active site   Charge relay system   by similarity   354   354
active site   Charge relay system   by similarity   467   467
short sequence motif   Prevents secretion from ER   potential   559   562

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MCLSALILVSLAAFTAGAG

Sequence

MCLSALILVSLAAFTAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVAV
FLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQDPVTGQIVND
LLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGA
STYDGLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALH
WVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGV
ALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLK
LNLFKLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGI
NKQEFGWILPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIE
KYLRDKDYTGRNKDQLLELIGDVVFGVPSVIVSRGHRDAGAPTYMYEFQY
SPSFSSEMKPDTVVGDHGDEIYSVFGAPILRGGTSEEEINLSKMMMKFWA
NFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWTELL
AKKQLPTEHTEL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website