Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

289

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P70375 (Created: 1997-11-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

FA7_MOUSE

Protein Name

Coagulation factor VII

Gene

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

446

Protein Mass [Da]

50276

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   24
chain   Factor VII light chain      42   193
chain   Factor VII heavy chain      194   446
disulfide bond      by similarity   58   63
disulfide bond      by similarity   91   102
disulfide bond      by similarity   96   111
disulfide bond      by similarity   113   122
disulfide bond      by similarity   132   143
disulfide bond      by similarity   139   153
disulfide bond      by similarity   155   168
disulfide bond      by similarity   176   303
disulfide bond      by similarity   200   205
disulfide bond      by similarity   219   235
disulfide bond      by similarity   351   370
disulfide bond      by similarity   381   409
domain   Gla      42   86
domain   EGF-like 1; calcium-binding   potential   87   123
domain   EGF-like 2      128   169
domain   Peptidase S1      194   433
modified residue   4-carboxyglutamate      47   47
modified residue   4-carboxyglutamate      48   48
modified residue   4-carboxyglutamate      55   55
modified residue   4-carboxyglutamate      57   57
modified residue   4-carboxyglutamate      60   60
modified residue   4-carboxyglutamate      61   61
modified residue   4-carboxyglutamate      66   66
modified residue   4-carboxyglutamate      67   67
modified residue   4-carboxyglutamate      70   70
modified residue   4-carboxyglutamate      76   76
modified residue   3-hydroxyaspartate   by similarity   104   104
glycosylation site   N-linked (GlcNAc...)   potential   186   186
glycosylation site   N-linked (GlcNAc...)   potential   244   244
site   Cleavage; by factor Xa, factor XIIa, factor IXa, or thrombin   by similarity   193   194
active site   Charge relay system   by similarity   234   234
active site   Charge relay system   by similarity   283   283
active site   Charge relay system   by similarity   385   385
propeptide      potential   25   41
binding site   Substrate   by similarity   379   379

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MVPQAHGLLLLCFLLQLQGPLGTA

Sequence

MVPQAHGLLLLCFLLQLQGPLGTAVFITQEEAHGVLHRQRRANSLLEELW
PGSLERECNEEQCSFEEAREIFKSPERTKQFWIVYSDGDQCASNPCQNGG
TCQDHLKSYVCFCLLDFEGRNCEKSKNEQLICANENGDCDQYCRDHVGTK
RTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVC
PKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMG
EHDFSEKDGDEQVRRVTQVIMPDKYIRGKINHDIALLRLHRPVTFTDYVV
PLCLPEKSFSENTLARIRFSRVSGWGQLLDRGATALELMSIEVPRLMTQD
CLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLT
GVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMDSKLQVGVFRLPLL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website