Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

295

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P26151 (Created: 1992-05-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

FCGR1_MOUSE

Protein Name

High affinity immunoglobulin gamma Fc receptor I

Gene

Fcgr1

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

404

Protein Mass [Da]

44888

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   24
chain   High affinity immunoglobulin gamma Fc receptor I      25   404
disulfide bond      by similarity   53   95
disulfide bond      by similarity   134   177
disulfide bond      by similarity   221   269
transmembrane region      potential   298   320
topological domain   Extracellular   potential   25   297
topological domain   Cytoplasmic   potential   321   404
domain   Ig-like C2-type 1      32   111
domain   Ig-like C2-type 2      117   194
domain   Ig-like C2-type 3      201   286
region of interest   Interaction with EPB41L2   by similarity   321   342
modified residue   Phosphotyrosine   by similarity   143   143
modified residue   Phosphotyrosine   by similarity   148   148
glycosylation site   N-linked (GlcNAc...)   potential   28   28
glycosylation site   N-linked (GlcNAc...)   potential   48   48
glycosylation site   N-linked (GlcNAc...)   potential   69   69
glycosylation site   N-linked (GlcNAc...)   potential   168   168
glycosylation site   N-linked (GlcNAc...)   potential   249   249

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MILTSFGDDMWLLTTLLLWVPVGG

Sequence

MILTSFGDDMWLLTTLLLWVPVGGEVVNATKAVITLQPPWVSIFQKENVT
LWCEGPHLPGDSSTQWFINGTAVQISTPSYSIPEASFQDSGEYRCQIGSS
MPSDPVQLQIHNDWLLLQASRRVLTEGEPLALRCHGWKNKLVYNVVFYRN
GKSFQFSSDSEVAILKTNLSHSGIYHCSGTGRHRYTSAGVSITVKELFTT
PVLRASVSSPFPEGSLVTLNCETNLLLQRPGLQLHFSFYVGSKILEYRNT
SSEYHIARAEREDAGFYWCEVATEDSSVLKRSPELELQVLGPQSSAPVWF
HILFYLSVGIMFSLNTVLYVKIHRLQREKKYNLEVPLVSEQGKKANSFQQ
VRSDGVYEEVTATASQTTPKEAPDGPRSSVGDCGPEQPEPLPPSDSTGAQ
TSQS

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website