Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

304

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P07589 (Created: 1988-04-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

FINC_BOVIN

Protein Name

Fibronectin

Gene

FN1

Organism Scientific

Bos taurus

Organism Common

Bovine

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Laurasiatheria
                  Cetartiodactyla
                    Ruminantia
                      Pecora
                        Bovidae
                          Bovinae
                            Bos

Protein Length [aa]

2478

Protein Mass [Da]

272154

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   32
chain   Fibronectin      33   2478
disulfide bond      by similarity   53   79
disulfide bond      by similarity   77   88
disulfide bond      by similarity   98   126
disulfide bond      by similarity   124   136
disulfide bond      by similarity   142   170
disulfide bond      by similarity   168   180
disulfide bond      by similarity   187   216
disulfide bond      by similarity   214   226
disulfide bond      by similarity   232   261
disulfide bond      by similarity   259   271
disulfide bond      by similarity   309   336
disulfide bond      by similarity   334   343
disulfide bond      by similarity   361   387
disulfide bond      by similarity   375   402
disulfide bond      by similarity   421   447
disulfide bond      by similarity   435   462
disulfide bond      by similarity   471   499
disulfide bond      by similarity   497   509
disulfide bond      by similarity   519   546
disulfide bond      by similarity   544   556
disulfide bond      by similarity   562   590
disulfide bond      by similarity   588   600
disulfide bond      by similarity   2298   2327
disulfide bond      by similarity   2325   2337
disulfide bond      by similarity   2343   2370
disulfide bond      by similarity   2368   2380
disulfide bond      by similarity   2387   2413
disulfide bond      by similarity   2411   2422
disulfide bond   Interchain (with C-2462)   by similarity   2459   2459
disulfide bond   Interchain (with C-2458)   by similarity   2463   2463
domain   Fibronectin type-I 1      51   91
domain   Fibronectin type-I 2      96   139
domain   Fibronectin type-I 3      140   183
domain   Fibronectin type-I 4      185   229
domain   Fibronectin type-I 5      230   274
domain   Fibronectin type-I 6      307   344
domain   Fibronectin type-II 1      356   404
domain   Fibronectin type-II 2      416   464
domain   Fibronectin type-I 7      469   517
domain   Fibronectin type-I 8      517   559
domain   Fibronectin type-I 9      560   603
domain   Fibronectin type-III 1      608   700
domain   Fibronectin type-III 2      721   810
domain   Fibronectin type-III 3      812   899
domain   Fibronectin type-III 4      907   996
domain   Fibronectin type-III 5      997   1085
domain   Fibronectin type-III 6      1093   1173
domain   Fibronectin type-III 7      1174   1266
domain   Fibronectin type-III 8; extra domain 1      1267   1357
domain   Fibronectin type-III 9      1358   1448
domain   Fibronectin type-III 10      1449   1538
domain   Fibronectin type-III 11      1539   1628
domain   Fibronectin type-III 12      1633   1722
domain   Fibronectin type-III 13; extra domain 2      1723   1812
domain   Fibronectin type-III 14      1815   1902
domain   Fibronectin type-III 15      1905   1993
domain   Fibronectin type-III 16      1994   2083
domain   Fibronectin type-III 17      2192   2282
domain   Fibronectin type-I 10      2296   2340
domain   Fibronectin type-I 11      2341   2383
domain   Fibronectin type-I 12      2385   2428
region of interest   Fibrin- and heparin-binding 1      53   273
region of interest   Collagen-binding      309   609
region of interest   Cell-attachment      1359   1632
region of interest   Heparin-binding 2      1813   2083
region of interest   Connecting strand 3 (CS-3) (V region)      2084   2203
region of interest   Fibrin-binding 2      2298   2429
modified residue   Pyrrolidone carboxylic acid   by similarity   33   33
modified residue   Sulfotyrosine   potential   877   877
modified residue   Sulfotyrosine   potential   882   882
modified residue   Phosphoserine   by similarity   905   905
modified residue   Sulfotyrosine   potential   2394   2394
modified residue   Phosphoserine   by similarity   2476   2476
glycosylation site   N-linked (GlcNAc...)   potential   431   431
glycosylation site   N-linked (GlcNAc...)   potential   529   529
glycosylation site   N-linked (GlcNAc...)   potential   543   543
glycosylation site   N-linked (GlcNAc...)   potential   878   878
glycosylation site   N-linked (GlcNAc...)   potential   1008   1008
glycosylation site   N-linked (GlcNAc...)   potential   1245   1245
glycosylation site   N-linked (GlcNAc...)   potential   1292   1292
glycosylation site   O-linked (GalNAc...)      2156   2156
glycosylation site   O-linked (GalNAc...)      2157   2157
glycosylation site   N-linked (GlcNAc...)   potential   2200   2200
short sequence motif   Cell attachment site   by similarity   1616   1618
short sequence motif   Cell attachment site   by similarity   2183   2185
DNA-binding region         908   1173
cross-link   Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-?)   by similarity   35   35
cross-link   Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-?)   by similarity   36   36
cross-link   Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-?)   by similarity   48   48

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MLGGPGPGLLLLLAVLSLGTAVPSAGASKSRR

Sequence

MLGGPGPGLLLLLAVLSLGTAVPSAGASKSRRQAQQIVQPQSPLTVSQSK
PGCYDNGKHYQINQQWERTYLGSALVCTCYGGSRGFNCESKPEPEETCFD
KYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYK
IGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDQAAGTSYVVGE
TWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKK
DNRGNLLQCICTGNGRGEWKCERHTSLQTTSAGSGSFTDVRTAIYQPQPH
PQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQ
TYGGNSNGEPCVLPFTYNGKTFYSCTTEGRQDGHLWCSTTSNYEQDQKYS
FCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT
QNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCV
GNGRGEWTCVAYSQLRDQCIVDGITYNVNDTFHKRHEEGHMLNCTCFGQG
RGRWKCDPVDQCQDSETRTFYQIGDSWEKYLQGVRYQCYCYGRGIGEWAC
QPLQTYPDTSGPVQVIITETPSQPNSHPIQWSAPESSHISKYILRWKPKN
SPDRWKEATIPGHLNSYTIKGLRPGVVYEGQLISVQHYGQREVTRFDFTT
TSTSPAVTSNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSG
FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYTVNVYEISEEGEQ
NLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPRAPITGYRIVYSPSV
EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETT
GVPRSDKVPPPRDLQFVEVTDVKITIMWTPPESPVTGYRVDVIPVNLPGE
HGQRLPVSRNTFAEVTGLSPGVTYHFKVFAVNQGRESKPLTAQQATKLDA
PTNLQFINETDTTVIVTWTPPRARIVGYRLTVGLTRGGQPKQYNVGPAAS
QYPLRNLQPGSEYAVSLVAVKGNQQSPRVTGVFTTLQPLGSIPHYNTEVT
ETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSESGSIVVSGLTPGVEY
VYTISVLRDGQERDAPIVKKVVTPLSPPTNLHLEANPDTGVLTVSWERST
TPDITGYRITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYT
VKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR
ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP
TTLTQQTAVPPPTDLRFTNVGPDTMRVTWAPPSSIELTNLLVRYSPVKNE
EDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQHESIPLRGRQKTAL
DSPSGIDFSDITANSFTVHWIAPRATITGYRIRHHPENMGGRPREDRVPP
SRNSITLTNLNPGTEYVVSIVALNSKEESLPLVGQQSTVSDVPRDLEVIA
ATPTSLLISWDAPAVTVRYYRITYGETGGSSPVQEFTVPGSKSTATISGL
KPGVDYTITVYAVTGRGDSPASSKPVSINYRTEIDKPSQMQVTDVQDNSI
SVRWLPSSSPVTGYRVTTAPKNGPGPSKTKTVGPDQTEMTIEGLQPTVEY
VVSVYAQNQNGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ
VSRYRVTYSSPEDGIHELFPAPDGEEETAELQGLRPGSEYTVSVVALHDD
MESQPLIGTQSTTIPAPTNLKFTQVTPTSLTAQWTAPNVQLTGYRVRVTP
KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV
TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAIPANGQTPIQ
RTIRPDVRSYTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAIDAPSN
LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
TITGLEPGTEYTIQVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGP
EILDVPSTVQKTPFITNPGYDTGNGIQLPGTSGQQPSLGQQMIFEEHGFR
RTTPPTTATPVRHRPRPYPPNVNEEIQIGHVPRGDVDHHLYPHVVGLNPN
ASTGQEALSQTTISWTPFQESSEYIISCHPVGIDEEPLQFRVPGTSASAT
LTGLTRGATYNIIVEAVKDQQRQKVREEVVTVGNSVDQGLSQPTDDSCFD
PYTVSHYAIGEEWERLSDSGFKLSCQCLGFGSGHFRCDSSKWCHDNGVNY
KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQW
QKEYLGAICSCTCFGGQRGWRCDNCRRPGAEPGNEGSTAHSYNQYSQRYH
QRTNTNVNCPIECFMPLDVQADREDSRE

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website