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Signal Peptide Database - Mammalia
Entry Details
ID
324
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P0C091 (Created: 2005-08-16 Updated: 2008-12-16)
UniProtKB/Swiss-Prot Entry Name
FREM3_HUMAN
Protein Name
FRAS1-related extracellular matrix protein 3
Gene
FREM3
Organism Scientific
Homo sapiens
Organism Common
Human
Lineage
Eukaryota
Metazoa
Chordata
Craniata
Vertebrata
Euteleostomi
Mammalia
Eutheria
Euarchontoglires
Primates
Haplorrhini
Catarrhini
Hominidae
Homo
Protein Length [aa]
2135
Protein Mass [Da]
237764
Features
Type
Description
Status
Start
End
signal peptide
potential
1
30
chain
FRAS1-related extracellular matrix protein 3
31
2135
domain
Calx-beta 1
1759
1858
domain
Calx-beta 2
1871
1981
domain
Calx-beta 3
1996
2102
glycosylation site
N-linked (GlcNAc...)
potential
846
846
glycosylation site
N-linked (GlcNAc...)
potential
1366
1366
glycosylation site
N-linked (GlcNAc...)
potential
1372
1372
glycosylation site
N-linked (GlcNAc...)
potential
1585
1585
repeat
CSPG 1
285
413
repeat
CSPG 2
414
524
repeat
CSPG 3
525
683
repeat
CSPG 4
684
811
repeat
CSPG 5
812
922
repeat
CSPG 6
923
1054
repeat
CSPG 7
1055
1173
repeat
CSPG 8
1174
1285
repeat
CSPG 9
1286
1403
repeat
CSPG 10
1404
1515
repeat
CSPG 11
1516
1633
repeat
CSPG 12
1634
1758
SP Length
30
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MAGASRHPTGTPRQLLVALACLLLSRPALQ
Sequence
MAGASRHPTGTPRQLLVALACLLLSRPALQ
GRASSLGTEPDPALYLPARG
ALDGTRPDGPSVLIANPGLRVPLGRSLWLDPLRDLVIGVQPGDRCEVTVL
DALPRLKGALSPRRFPCTFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTH
TLVLPFTLAVDLVFSQLELVTRNRPLVVEKLRSWSRAIDRRVLDFASLKS
GATATRRCRLTPLPHEDGPLPKYGRLVDAVGAPLPRGKGVDCEAFLRAGV
RYQHTATSSPNRDYVPMMVELLGPEGQDAGSAGV
LVREHFQLLVRIRGGA
ENTPPRPSFMATMMMEVDPLVLTALTPDALAAEDVESDPGDLVFNILNAP
THPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKIAYQPPAENSHGER
LFQLELEVVDGDG
AASDPFAFMVTVKSMNTLVPVASHNRGLVLFEGQSRP
LSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAA
GRVVYQHDGSNTYSDNIIFRMEDG
HHQVDFLFPLTILPVDDEPPMVNTNT
GLSLTEGQVVQISPFVLSATDIDSEDSTIHFVLENQPLKGNEEEPQWELA
PGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDI
MEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPP
NLSKQHIFTIKVQPVDI
LSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTD
TDGNHQVRAGEIVLTDSPDTLIMHFTQAQVNQHKVAYQPPQKLGIAPRVV
QFTYQVEDAAG
NSVPGTFTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSN
ELHVTDPDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSV
SYQHGRDQTTTSDTFHLEVSDG
VHHIPITIPISVHPNVANRSPRISLRSS
SLLDVSIDVLENKATEITMGVIHGKRKDVGDLMLSFIVKDSPKLGTILVN
GLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFSLLSKDSYQWVVGNS
IIEK
VQVQVTVLPVDNVGPKVFVGESFIVYEGEKNSLTLQHLHVEDVDTH
QDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQVRHINY
VQSIHKGVEPQEDQFTFYCSDGI
NFSPNVFFPIIILPTNDEQPKLFAHEF
KVLEGMSLVIDTQLLNGADADLPPNEHFQLTALPRHGRIIQQLATGSQPI
HSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDG
KHTTHRKVPIVVTLV
DDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQ
GLLQRLRKPRGEVRNNLTLGMNFTQDEINRGLICYIHTGQEGIVDIIKFD
VTD
GVNTLTDHYFYVIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSD
INSSDEHHFSITRAPSLGHLESSDYAGEPIASFTQLQLASNKISYVHTSN
DEKKMDSFEFQVIGE
LYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQ
LITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVTTFTKQDLNK
NLIYKHDGSETTEDSFSLTVTDGTHTDFYVLPD
TALATHKPQVMRVQIRS
LDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKV
TRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDIFYFS
VEDNGGNK
LTNQPFHLNWAWICLEKEYYIVDEDSTFLEVTLTRRGYLGET
SFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETS
ETFQIILS
EPLMAVLEFPEM
ATVEIVDPGDESTVYIPEAEYKIEEDIGEL
LIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILH
FDKNETQKTCQVLIIDDSLYEEEESFSVSLR
LPVGGQLGARFPTT
KVTIL
ADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSE
QESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELL
LQ
MPMGAVLGEPNKTTIFIEDTITDCKQSACSSFD
Original
MAGASRHPTGTPRQLLVALACLLLSRPALQGRASSLGTEPDPALYLPARG
ALDGTRPDGPSVLIANPGLRVPLGRSLWLDPLRDLVIGVQPGDRCEVTVL
DALPRLKGALSPRRFPCTFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTH
TLVLPFTLAVDLVFSQLELVTRNRPLVVEKLRSWSRAIDRRVLDFASLKS
GATATRRCRLTPLPHEDGPLPKYGRLVDAVGAPLPRGKGVDCEAFLRAGV
RYQHTATSSPNRDYVPMMVELLGPEGQDAGSAGVLVREHFQLLVRIRGGA
ENTPPRPSFMATMMMEVDPLVLTALTPDALAAEDVESDPGDLVFNILNAP
THPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKIAYQPPAENSHGER
LFQLELEVVDGDGAASDPFAFMVTVKSMNTLVPVASHNRGLVLFEGQSRP
LSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAA
GRVVYQHDGSNTYSDNIIFRMEDGHHQVDFLFPLTILPVDDEPPMVNTNT
GLSLTEGQVVQISPFVLSATDIDSEDSTIHFVLENQPLKGNEEEPQWELA
PGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDI
MEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLSKQHIFTIKVQPVDI
LSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTD
TDGNHQVRAGEIVLTDSPDTLIMHFTQAQVNQHKVAYQPPQKLGIAPRVV
QFTYQVEDAAGNSVPGTFTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSN
ELHVTDPDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSV
SYQHGRDQTTTSDTFHLEVSDGVHHIPITIPISVHPNVANRSPRISLRSS
SLLDVSIDVLENKATEITMGVIHGKRKDVGDLMLSFIVKDSPKLGTILVN
GLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFSLLSKDSYQWVVGNS
IIEKVQVQVTVLPVDNVGPKVFVGESFIVYEGEKNSLTLQHLHVEDVDTH
QDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQVRHINY
VQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEF
KVLEGMSLVIDTQLLNGADADLPPNEHFQLTALPRHGRIIQQLATGSQPI
HSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVPIVVTLV
DDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQ
GLLQRLRKPRGEVRNNLTLGMNFTQDEINRGLICYIHTGQEGIVDIIKFD
VTDGVNTLTDHYFYVIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSD
INSSDEHHFSITRAPSLGHLESSDYAGEPIASFTQLQLASNKISYVHTSN
DEKKMDSFEFQVIGELYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQ
LITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVTTFTKQDLNK
NLIYKHDGSETTEDSFSLTVTDGTHTDFYVLPDTALATHKPQVMRVQIRS
LDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKV
TRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDIFYFS
VEDNGGNKLTNQPFHLNWAWICLEKEYYIVDEDSTFLEVTLTRRGYLGET
SFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETS
ETFQIILSEPLMAVLEFPEMATVEIVDPGDESTVYIPEAEYKIEEDIGEL
LIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILH
FDKNETQKTCQVLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTIL
ADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSE
QESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELL
LQMPMGAVLGEPNKTTIFIEDTITDCKQSACSSFD
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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© 2007-2017
Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11
