Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

331

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9Z0U4 (Created: 2001-01-11 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

GABR1_RAT

Protein Name

Gamma-aminobutyric acid type B receptor subunit 1

Gene

Gabbr1

Organism Scientific

Rattus norvegicus

Organism Common

Rat

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Rattus

Protein Length [aa]

991

Protein Mass [Da]

111534

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   16
chain   Gamma-aminobutyric acid type B receptor subunit 1      17   991
disulfide bond         99   144
disulfide bond         130   156
transmembrane region   1   potential   591   611
transmembrane region   2   potential   631   651
transmembrane region   3   potential   667   687
transmembrane region   4   potential   710   730
transmembrane region   5   potential   798   818
transmembrane region   6   potential   835   855
transmembrane region   7   potential   864   884
topological domain   Extracellular   potential   17   590
topological domain   Cytoplasmic   potential   612   630
topological domain   Extracellular   potential   652   666
topological domain   Cytoplasmic   potential   688   709
topological domain   Extracellular   potential   731   797
topological domain   Cytoplasmic   potential   819   834
topological domain   Extracellular   potential   856   863
topological domain   Cytoplasmic   potential   885   991
domain   Sushi 1      29   95
domain   Sushi 2      97   158
region of interest   Interaction with ATF4      918   946
modified residue   Phosphothreonine   by similarity   960   960
glycosylation site   N-linked (GlcNAc...)   potential   23   23
glycosylation site   N-linked (GlcNAc...)   potential   83   83
glycosylation site   N-linked (GlcNAc...)   potential   408   408
glycosylation site   N-linked (GlcNAc...)   potential   439   439
glycosylation site   N-linked (GlcNAc...)   potential   481   481
glycosylation site   N-linked (GlcNAc...)   potential   501   501
glycosylation site   N-linked (GlcNAc...)   potential   513   513
strand         109   115
strand         125   130
strand         134   136
strand         141   144
strand         146   151
strand         156   158
helix         102   104
splice variant   (in isoform 1B, isoform 1C, isoform 1D)      0   0
splice variant   (in isoform 1D)      0   0
splice variant   (in isoform 1A, isoform 1B, isoform 1D)      771   801
mutagenesis site   Decrease in the affinity for GABA      0   0
mutagenesis site   No change in the affinity for GABA      0   0
mutagenesis site   No change in the affinity for GABA      0   0
coiled-coil region      potential   901   955

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MLLLLLVPLFLRPLGA

Sequence

MLLLLLVPLFLRPLGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQV
KAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICS
KSYLTLENGKVFLTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQGQWS
TPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNS
RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVST
LVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF
EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV
KNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWF
KTYDPSINCTVEEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLT
KRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYN
NQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIG
YYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSL
GIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDG
YHIGRSQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW
RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDID
VSILPQLEHCSSKKMNTWLGELWSFAVSSDVQRRATVGGDSPICVWPAPE
SIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA
PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSET
QDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQ
QLRSRRHPPTPPDPSGGLPRGPSEPPDRLSCDGSRVHLLYK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website