Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

332

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P54803 (Created: 1996-10-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

GALC_HUMAN

Protein Name

Galactocerebrosidase

Gene

GALC

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

669

Protein Mass [Da]

75147

Features

TypeDescriptionStatusStartEnd
signal peptide         1   26
chain   Galactocerebrosidase      27   669
glycosylation site   N-linked (GlcNAc...)   potential   127   127
glycosylation site   N-linked (GlcNAc...)   potential   363   363
glycosylation site   N-linked (GlcNAc...)   potential   387   387
glycosylation site   N-linked (GlcNAc...)   potential   540   540
glycosylation site   N-linked (GlcNAc...)   potential   543   543
glycosylation site   N-linked (GlcNAc...)   potential   586   586
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; bilateral cherry red spots)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD; Arab patients)      0   0
sequence variant   (in GLD; loss of activity)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD; adult)      0   0
sequence variant   (in significant reduction of activity when associated with T-546; dbSNP:rs421262)      0   0
sequence variant   (in GLD; adult)      0   0
sequence variant   (in GLD; infantile; Druze patients)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; belgian patient)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in common polymorphism; dbSNP:rs398607)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in dbSNP:rs1805079)      0   0
sequence variant   (in GLD; adult)      0   0
sequence variant   (in GLD; adult)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; adult; reduction of activity; when associated with V-289)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in dbSNP:rs1805078)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; infantile; significant reduction of activity)      0   0
sequence variant   (in GLD)      0   0
sequence variant   (in GLD; late infantile)      0   0
sequence variant         0   0
splice variant   (in isoform 2)      0   0
splice variant   (in isoform 2)      392   669

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MTAAAGSAGRAAVPLLLCALLAPGGA

Sequence

MTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGAVSGGGA
TSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSH
MHYALDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYV
NLQLTAYYVVTWIVGAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQ
GLQRVKIIASDNLWESISASMLLDAELFKVVDVIGAHYPGTHSAKDAKLT
GKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGYMTSTIAWNLVASYYEQ
LPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKTVGHLEK
GGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGS
FSEIPELQVWYTKLGKTSERFLFKQLDSLWLLDSDGSFTLSLHEDELFTL
TTLTTGRKGSYPLPPKSQPFPSTYKDDFNVDYPFFSEAPNFADQTGVFEY
FTNIEDPGEHHFTLRQVLNQRPITWAADASNTISIIGDYNWTNLTIKCDV
YIETPDTGGVFIAGRVNKGGILIRSARGIFFWIFANGSYRVTGDLAGWII
YALGRVEVTAKKWYTLTLTIKGHFASGMLNDKSLWTDIPVNFPKNGWAAI
GTHSFEFAQFDNFLVEATR

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website